Trifluridine EP Impurity B

Name: Trifluridine EP Impurity B
Brand: Vaqora Chemicals
SKU: VQ-028522

About Trifluridine EP Impurity B

Vaqora Chemicals supplies Trifluridine EP Impurity B, a pharmacopeial impurity of Trifluridine registered under CAS number 54-20-6. Formula C5H3F3N2O2, molecular weight 180.08 g/mol. The IUPAC name is 5-(trifluoromethyl)-1H-pyrimidine-2,4-dione. Common synonyms include 5-(Trifluoromethyl)uracil and Trifluridine - Impurity B.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Trifluridine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Trifluridine

View every impurity, metabolite and intermediate we list for Trifluridine.

Trifluridine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Trifluridine EP Impurity B
Catalogue No.	VQ-028522
CAS Number	54-20-6
IUPAC name	5-(trifluoromethyl)-1H-pyrimidine-2,4-dione
Molecular formula	C₅H₃F₃N₂O₂
Molecular weight	180.08 g/mol
Exact mass	180.0147
Grade	Reference Standard
HSN code	38229090
InChIKey	LMNPKIOZMGYQIU-UHFFFAOYSA-N
SMILES	C1=C(C(=O)NC(=O)N1)C(F)(F)F
PubChem CID	5899

Physical properties
Physical form	Solid
H-bond donors / acceptors	2 / 5
TPSA	58.2 Å²
Synonyms	5-(Trifluoromethyl)uracil, Trifluridine - Impurity B, 5-TFMU, Trifluorothymine, 5-Trifluoromethyluracil, 5-(trifluoromethyl)pyrimidine-2,4(1H,3H)-dione, 2,4(1H,3H)-Pyrimidinedione, 5-(trifluoromethyl)-, 5-(trifluoromethyl)-1,2,3,4-tetrahydropyrimidine-2,4-dione, 5-Trifluoromethyl-1H-pyrimidine-2,4-dione, 5-trifluoromethyl-uracil, 5-(trifluoromethyl)-1,3-dihydropyrimidine-2,4-dione

Safety & hazard information (GHS)

Toxic

Harmful / irritant

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P316, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Trifluridine EP Impurity B?

The CAS Registry Number of Trifluridine EP Impurity B is 54-20-6. It is also known as 5-(Trifluoromethyl)uracil, Trifluridine - Impurity B, 5-TFMU.

What is the molecular formula and molecular weight of Trifluridine EP Impurity B?

Trifluridine EP Impurity B has the molecular formula C5H3F3N2O2 and a molecular weight of 180.08 g/mol. Its IUPAC name is 5-(trifluoromethyl)-1H-pyrimidine-2,4-dione.

What is Trifluridine EP Impurity B used for?

Trifluridine EP Impurity B is supplied as a characterised reference material related to Trifluridine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Trifluridine EP Impurity B can I order?

We supply Trifluridine EP Impurity B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Trifluridine EP Impurity B?

Yes. Every lot of Trifluridine EP Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Trifluridine EP Impurity B be shipped internationally?

Yes. Trifluridine EP Impurity B is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.