Cyclomethicone 5

Name: Cyclomethicone 5
Brand: Vaqora Chemicals
SKU: VQ-036468

About Cyclomethicone 5

Listed under CAS 541-02-6, Cyclomethicone 5 is a high-purity reference standard of Cyclomethicone available from Vaqora Chemicals. Its molecular formula is C10H30O5Si5 and its molecular weight is 370.77 g/mol. Systematically, it is named 2,2,4,4,6,6,8,8,10,10-decamethyl-1,3,5,7,9,2,4,6,8,10-pentaoxapentasilecane. It is also known as Decamethylcyclopentasiloxane or Dimethylsiloxane pentamer.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Laboratories use this Cyclomethicone standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Cyclomethicone 5 in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Cyclomethicone

View every impurity, metabolite and intermediate we list for Cyclomethicone.

Cyclomethicone impurities

Specifications & identifiers

Chemical identifiers
Product name	Cyclomethicone 5
Catalogue No.	VQ-036468
CAS Number	541-02-6
IUPAC name	2,2,4,4,6,6,8,8,10,10-decamethyl-1,3,5,7,9,2,4,6,8,10-pentaoxapentasilecane
Molecular formula	C₁₀H₃₀O₅Si₅
Molecular weight	370.77 g/mol
Exact mass	370.094
Grade	Reference Standard
HSN code	38229090
InChIKey	XMSXQFUHVRWGNA-UHFFFAOYSA-N
SMILES	C[Si]1(O[Si](O[Si](O[Si](O[Si](O1)(C)C)(C)C)(C)C)(C)C)C
PubChem CID	10913

Physical properties
Physical form	Solid
H-bond donors / acceptors	0 / 5
TPSA	46.2 Å²
Synonyms	Decamethylcyclopentasiloxane, Dimethylsiloxane pentamer, Dow corning 345, Cyclic dimethylsiloxane pentamer, NUC silicone VS 7158, Silicon SF 1202, Ciclopentasiloxane, KF 995, Cyclopentasiloxane, 2,2,4,4,6,6,8,8,10,10-decamethyl-, KF-995, Lightening Serum, Smooth and Soft Cuticles

Safety & hazard information (GHS)

Health hazard

Signal word: Warning

Hazard statements

H227Combustible liquid
H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements: P210, P260, P280, P319, P370 + P378, P403, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Cyclomethicone 5?

The CAS Registry Number of Cyclomethicone 5 is 541-02-6. It is also known as Decamethylcyclopentasiloxane, Dimethylsiloxane pentamer, Dow corning 345.

What is the molecular formula and molecular weight of Cyclomethicone 5?

Cyclomethicone 5 has the molecular formula C10H30O5Si5 and a molecular weight of 370.77 g/mol. Its IUPAC name is 2,2,4,4,6,6,8,8,10,10-decamethyl-1,3,5,7,9,2,4,6,8,10-pentaoxapentasilecane.

What is Cyclomethicone 5 used for?

Cyclomethicone 5 is supplied as a characterised reference material related to Cyclomethicone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Cyclomethicone 5 can I order?

We supply Cyclomethicone 5 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Cyclomethicone 5?

Yes. Every lot of Cyclomethicone 5 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Cyclomethicone 5 be shipped internationally?

Yes. Cyclomethicone 5 is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.