Nimesulide EP Impurity D

About Nimesulide EP Impurity D

Nimesulide EP Impurity D is a pharmacopeial impurity of Nimesulide carrying the CAS registry number 5422-92-4. The compound has the formula C12H10N2O3, corresponding to a molecular weight of 230.22 g/mol. Its systematic (IUPAC) name is 4-nitro-2-phenoxyaniline. It is also known as 4-Nitro-2-phenoxybenzenamine or (4-Nitro-2-phenoxyphenyl)amine.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

As a characterised impurity of Nimesulide, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Nimesulide

View every impurity, metabolite and intermediate we list for Nimesulide.

Nimesulide impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Nimesulide EP Impurity D
Catalogue No.	VQ-006535
CAS Number	5422-92-4
IUPAC name	4-nitro-2-phenoxyaniline
Molecular formula	C₁₂H₁₀N₂O₃
Molecular weight	230.22 g/mol
Exact mass	230.0691
Grade	Reference Standard
HSN code	38229090
InChIKey	CGQKBVHAWXBMCL-UHFFFAOYSA-N
SMILES	C1=CC=C(C=C1)OC2=C(C=CC(=C2)[N+](=O)[O-])N
PubChem CID	223329

Physical properties
Physical form	Solid
LogP (XLogP3)	3
H-bond donors / acceptors	1 / 4
TPSA	81.1 Å²
Synonyms	4-Nitro-2-phenoxybenzenamine, (4-Nitro-2-phenoxyphenyl)amine, 1-Amino-2-phenoxy-4-nitrobenzene, 2-Amino-5-nitrodiphenyl ether, 2-Phenoxy-4-nitroaniline, Nimesulide Impurity D, Benzenamine, 4-nitro-2-phenoxy-, 4-nitro-2-phenoxy-aniline, 4-Nitro-2-phenoxyaniline, Nimesulide Imp. D (EP), Nimesulide impurity D CRS

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Nimesulide EP Impurity D?

The CAS Registry Number of Nimesulide EP Impurity D is 5422-92-4. It is also known as 4-Nitro-2-phenoxybenzenamine, (4-Nitro-2-phenoxyphenyl)amine, 1-Amino-2-phenoxy-4-nitrobenzene.

What is the molecular formula and molecular weight of Nimesulide EP Impurity D?

Nimesulide EP Impurity D has the molecular formula C12H10N2O3 and a molecular weight of 230.22 g/mol. Its IUPAC name is 4-nitro-2-phenoxyaniline.

What is Nimesulide EP Impurity D used for?

Nimesulide EP Impurity D is supplied as a characterised reference material related to Nimesulide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Nimesulide EP Impurity D can I order?

We supply Nimesulide EP Impurity D in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Nimesulide EP Impurity D?

Yes. Every lot of Nimesulide EP Impurity D is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Nimesulide EP Impurity D be shipped internationally?

Yes. Nimesulide EP Impurity D is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.