Sumatriptan EP Impurity A

About Sumatriptan EP Impurity A

Sumatriptan EP Impurity A is a pharmacopeial impurity of Sumatriptan carrying the CAS registry number 545338-89-4 with a typical assay of 44%. Formula C27H37N5O2S, molecular weight 495.7 g/mol. Common synonyms include Sumatriptan succinate specified impurity A.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

This Sumatriptan impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Sumatriptan

View every impurity, metabolite and intermediate we list for Sumatriptan.

Sumatriptan impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Sumatriptan EP Impurity A
Catalogue No.	VQ-006699
CAS Number	545338-89-4
Other CAS	2771193-10-1
IUPAC name	1-[3-[2-(dimethylamino)ethyl]-2-[[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]methyl]-1H-indol-5-yl]-N-methylmethanesulfonamide
Molecular formula	C₂₇H₃₇N₅O₂S
Molecular weight	495.7 g/mol
Exact mass	495.2668
Grade	Reference Standard
Purity / assay	44%
HSN code	38229090
InChIKey	UVOHQDUMFGSNEJ-UHFFFAOYSA-N
SMILES	CNS(=O)(=O)CC1=CC2=C(C=C1)NC(=C2CCN(C)C)CC3=CC4=C(C=C3)NC=C4CCN(C)C
PubChem CID	12074066

Physical properties
Physical form	Solid
LogP (XLogP3)	3.3
H-bond donors / acceptors	3 / 5
TPSA	92.6 Å²

Safety & hazard information (GHS)

Health hazard

Signal word: Danger

Hazard statements

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

Precautionary statements: P233, P260, P271, P284, P304 + P340, P342 + P316, P403, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Sumatriptan EP Impurity A?

The CAS Registry Number of Sumatriptan EP Impurity A is 545338-89-4. It is also known as 2-[[3-[2-(Dimethylamino)ethyl]-1H-indol-5-yl]methyl] Sumatriptan, Sumatriptan succinate specified impurity A, 2-[[3-[2-(Dimethylamino)ethyl]-1H-indol-5-yl]methyl] Sumatriptan (>90%).

What is the molecular formula and molecular weight of Sumatriptan EP Impurity A?

Sumatriptan EP Impurity A has the molecular formula C27H37N5O2S and a molecular weight of 495.7 g/mol. Its IUPAC name is 1-[3-[2-(dimethylamino)ethyl]-2-[[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]methyl]-1H-indol-5-yl]-N-methylmethanesulfonamide.

What is Sumatriptan EP Impurity A used for?

Sumatriptan EP Impurity A is supplied as a characterised reference material related to Sumatriptan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Sumatriptan EP Impurity A can I order?

We supply Sumatriptan EP Impurity A in Reference Standard (44%) grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Sumatriptan EP Impurity A?

Yes. Every lot of Sumatriptan EP Impurity A is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Sumatriptan EP Impurity A be shipped internationally?

Yes. Sumatriptan EP Impurity A is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.