N-Nitroso-2-Pyrrolidinone

Name: N-Nitroso-2-Pyrrolidinone
Brand: Vaqora Chemicals
SKU: VQ-023376

About N-Nitroso-2-Pyrrolidinone

N-Nitroso-2-Pyrrolidinone (CAS 54634-49-0) is a nitrosamine impurity of Piracetam offered by Vaqora Chemicals. Its molecular formula is C4H6N2O2 and its molecular weight is 114.1 g/mol. The IUPAC name is 1-nitrosopyrrolidin-2-one. Alternative names: 2-Pyrrolidinone, 1-nitroso- and 1-Nitroso-2-pyrrolidinone.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Laboratories use this nitrosamine standard to develop and validate highly sensitive LC-MS/MS methods, to confirm limits of detection and to document nitrosamine risk assessments in regulatory submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, N-Nitroso-2-Pyrrolidinone is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Nitrosamine risk assessment
Trace LC-MS/MS quantitation
Method validation (AMV)
Regulatory submissions

Industries

Related to Piracetam

View every impurity, metabolite and intermediate we list for Piracetam.

Piracetam impurities

Specifications & identifiers

Chemical identifiers
Product name	N-Nitroso-2-Pyrrolidinone
Catalogue No.	VQ-023376
CAS Number	54634-49-0
IUPAC name	1-nitrosopyrrolidin-2-one
Molecular formula	C₄H₆N₂O₂
Molecular weight	114.1 g/mol
Exact mass	114.0429
Grade	Reference Standard
HSN code	38229090
InChIKey	KLZYCEYOOVIITI-UHFFFAOYSA-N
SMILES	C1CC(=O)N(C1)N=O
PubChem CID	93298

Physical properties
Physical form	Solid
LogP (XLogP3)	-1.4
H-bond donors / acceptors	0 / 3
TPSA	49.7 Å²
Synonyms	2-Pyrrolidinone, 1-nitroso-, 1-Nitroso-2-pyrrolidinone, N-Nitroso-2-pyrrolidone, 2-Pyrrolidinone,1-nitroso-, N-Nitroso 2-pyrrolidone

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Nitroso-2-Pyrrolidinone?

The CAS Registry Number of N-Nitroso-2-Pyrrolidinone is 54634-49-0. It is also known as 2-Pyrrolidinone, 1-nitroso-, 1-Nitroso-2-pyrrolidinone, N-Nitroso-2-pyrrolidone.

What is the molecular formula and molecular weight of N-Nitroso-2-Pyrrolidinone?

N-Nitroso-2-Pyrrolidinone has the molecular formula C4H6N2O2 and a molecular weight of 114.1 g/mol. Its IUPAC name is 1-nitrosopyrrolidin-2-one.

What is N-Nitroso-2-Pyrrolidinone used for?

N-Nitroso-2-Pyrrolidinone is supplied as a characterised reference material related to Piracetam. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Nitroso-2-Pyrrolidinone can I order?

We supply N-Nitroso-2-Pyrrolidinone in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Nitroso-2-Pyrrolidinone?

Yes. Every lot of N-Nitroso-2-Pyrrolidinone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Nitroso-2-Pyrrolidinone be shipped internationally?

Yes. We export N-Nitroso-2-Pyrrolidinone worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.