Estriol EP Impurity F

About Estriol EP Impurity F

Estriol EP Impurity F is a pharmacopeial impurity of Estriol carrying the CAS registry number 547-81-9. The compound has the formula C18H24O3, corresponding to a molecular weight of 288.4 g/mol. Systematically, it is named (8R,9S,13S,14S,16S,17R)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,16,17-triol. It is also known as 16-Epiestriol or Estriol - Impurity F.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Estriol to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Estriol

View every impurity, metabolite and intermediate we list for Estriol.

Estriol impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Estriol EP Impurity F
Catalogue No.	VQ-022560
CAS Number	547-81-9
IUPAC name	(8R,9S,13S,14S,16S,17R)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,16,17-triol
Molecular formula	C₁₈H₂₄O₃
Molecular weight	288.4 g/mol
Exact mass	288.1725
Grade	Reference Standard
HSN code	38229090
InChIKey	PROQIPRRNZUXQM-ZMSHIADSSA-N
SMILES	C[C@]12CC[C@H]3[C@H]([C@@H]1C[C@@H]([C@@H]2O)O)CCC4=C3C=CC(=C4)O
PubChem CID	68929

Physical properties
Physical form	Solid
LogP (XLogP3)	2.5
H-bond donors / acceptors	3 / 3
TPSA	60.7 Å²
Synonyms	16-Epiestriol, Estriol - Impurity F, Epiestriol, Epioestriol, Estra-1,3,5(10)-triene-3,16beta,17beta-triol, Actriol, 16-epi-Estriol, 16b-hydroxyestradiol, 16-Epiestratriol, 16beta-Hydroxyestradiol, 16b,17b-Estriol, Estra-1,3.5(10)-triene-3,16beta,17beta-triol

Safety & hazard information (GHS)

Health hazard

Signal word: Danger

Hazard statements

H350May cause cancer
H360May damage fertility or the unborn child
H372Causes damage to organs through prolonged or repeated exposure

Precautionary statements: P203, P260, P264, P270, P280, P318, P319, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Estriol EP Impurity F?

The CAS Registry Number of Estriol EP Impurity F is 547-81-9. It is also known as 16-Epiestriol, Estriol - Impurity F, Epiestriol.

What is the molecular formula and molecular weight of Estriol EP Impurity F?

Estriol EP Impurity F has the molecular formula C18H24O3 and a molecular weight of 288.4 g/mol. Its IUPAC name is (8R,9S,13S,14S,16S,17R)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,16,17-triol.

What is Estriol EP Impurity F used for?

Estriol EP Impurity F is supplied as a characterised reference material related to Estriol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Estriol EP Impurity F can I order?

We supply Estriol EP Impurity F in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Estriol EP Impurity F?

Yes. Every lot of Estriol EP Impurity F is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Estriol EP Impurity F be shipped internationally?

Yes. Estriol EP Impurity F is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.