Clobetasol Propionate EP Impurity A

Name: Clobetasol Propionate EP Impurity A
Brand: Vaqora Chemicals
SKU: VQ-020929

About Clobetasol Propionate EP Impurity A

Clobetasol Propionate EP Impurity A (CAS 5534-13-4) is a pharmacopeial impurity of Betamethasone offered by Vaqora Chemicals. Formula C25H33FO6, molecular weight 448.5 g/mol. Alternative names: Betamethasone 17 -Propionate and Betamethasone 17-Propionate.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Danger” with 2 hazard statements. Review the Safety Data Sheet before use.

This Betamethasone impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer Clobetasol Propionate EP Impurity A in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Betamethasone

View every impurity, metabolite and intermediate we list for Betamethasone.

Betamethasone impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Clobetasol Propionate EP Impurity A
Catalogue No.	VQ-020929
CAS Number	5534-13-4
IUPAC name	[(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate
Molecular formula	C₂₅H₃₃FO₆
Molecular weight	448.5 g/mol
Exact mass	448.2261
Grade	Reference Standard
HSN code	38229090
InChIKey	ITYMTTQVNYAJAA-XGQKBEPLSA-N
SMILES	CCC(=O)O[C@@]1([C@H](C[C@@H]2[C@@]1(C[C@@H]([C@]3([C@H]2CCC4=CC(=O)C=C[C@@]43C)F)O)C)C)C(=O)CO
PubChem CID	93007

Physical properties
Physical form	Solid
LogP (XLogP3)	2.6
H-bond donors / acceptors	2 / 7
TPSA	101 Å²
Synonyms	Betamethasone 17 -Propionate, Betamethasone 17-Propionate, Betamethasone Dipropionate - Impurity B, Betamethasone Dipropionate EP Impurity B, Clobetasol Propionate - Impurity A, Betamethasone 17alpha-Propionate, 9-Fluoro-11beta,21-dihydroxy-16beta-methyl-3,20-dioxopregna-1,4-dien-17-yl propanoate, 9-Fluoro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 17-propionate, 9-Fluoro-11b,21-dihydroxy-16b-methyl-3,20- dioxopregna-1,4-dien-17-yl propanoate, (11b,16b)-9-Fluoro-11,21-dihydroxy-16-methyl-17-(1-oxopropoxy)pregna-1,4-diene-3,20-dione

Safety & hazard information (GHS)

Health hazard

Signal word: Danger

Hazard statements

H360May damage fertility or the unborn child
H412Harmful to aquatic life with long lasting effects

Precautionary statements: P203, P273, P280, P318, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Clobetasol Propionate EP Impurity A?

The CAS Registry Number of Clobetasol Propionate EP Impurity A is 5534-13-4. It is also known as Betamethasone 17 -Propionate, Betamethasone 17-Propionate, Betamethasone Dipropionate - Impurity B.

What is the molecular formula and molecular weight of Clobetasol Propionate EP Impurity A?

Clobetasol Propionate EP Impurity A has the molecular formula C25H33FO6 and a molecular weight of 448.5 g/mol.

What is Clobetasol Propionate EP Impurity A used for?

Clobetasol Propionate EP Impurity A is supplied as a characterised reference material related to Betamethasone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Clobetasol Propionate EP Impurity A can I order?

We supply Clobetasol Propionate EP Impurity A in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Clobetasol Propionate EP Impurity A?

Yes. Every lot of Clobetasol Propionate EP Impurity A is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Clobetasol Propionate EP Impurity A be shipped internationally?

Yes. Clobetasol Propionate EP Impurity A is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.