N-Nitroso-4-Piperidone

About N-Nitroso-4-Piperidone

N-Nitroso-4-Piperidone is a nitrosamine impurity standard carrying the CAS registry number 55556-91-7 at a purity of 96.83%. Formula C5H8N2O2, molecular weight 128.13 g/mol. Systematically, it is named 1-nitrosopiperidin-4-one. Alternative names: 1-Nitroso-4-piperidinone and 4-Keto-N-Nitrosopiperidine.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

It is used as a reference standard for trace-level detection and quantitation of nitrosamine impurities by LC-MS/MS or GC-MS, supporting nitrosamine risk assessments, method validation (AMV) and regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. Stock is available for quick dispatch.

Typical applications

Nitrosamine risk assessment
Trace LC-MS/MS quantitation
Method validation (AMV)
Regulatory submissions

Industries

Specifications & identifiers

Chemical identifiers
Product name	N-Nitroso-4-Piperidone
Catalogue No.	VQ-006972
CAS Number	55556-91-7
IUPAC name	1-nitrosopiperidin-4-one
Molecular formula	C₅H₈N₂O₂
Molecular weight	128.13 g/mol
Exact mass	128.0586
Grade	Reference Standard
Purity / assay	96.83%
HSN code	38229090
InChIKey	ADLADNOVIJYIMA-UHFFFAOYSA-N
SMILES	C1CN(CCC1=O)N=O
PubChem CID	41469

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.5
H-bond donors / acceptors	0 / 4
TPSA	49.7 Å²
Synonyms	1-Nitroso-4-piperidinone, 4-Keto-N-Nitrosopiperidine, N-Nitroso-4-piperidinone, Nitroso-4-piperidone, 1-Nitroso-4-piperidone, Nitroso-4-piperidinone, 4-Piperidone, 1-nitroso-, NN-4-P, 4-Piperidinone, 1-nitroso-, 1-Nitroso-4-piperidinone #, 5-21-06-00429 (Beilstein Handbook Reference)

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H351Suspected of causing cancer

Precautionary statements: P203, P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P318, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Nitroso-4-Piperidone?

The CAS Registry Number of N-Nitroso-4-Piperidone is 55556-91-7. It is also known as 1-Nitroso-4-piperidinone, 4-Keto-N-Nitrosopiperidine, N-Nitroso-4-piperidinone.

What is the molecular formula and molecular weight of N-Nitroso-4-Piperidone?

N-Nitroso-4-Piperidone has the molecular formula C5H8N2O2 and a molecular weight of 128.13 g/mol. Its IUPAC name is 1-nitrosopiperidin-4-one.

Which grade and pack sizes of N-Nitroso-4-Piperidone can I order?

We supply N-Nitroso-4-Piperidone in Reference Standard (96.83%) grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Nitroso-4-Piperidone?

Yes. Every lot of N-Nitroso-4-Piperidone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Nitroso-4-Piperidone be shipped internationally?

Yes. N-Nitroso-4-Piperidone is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.