1,4-Dinitroso-1,4-diazepane

About 1,4-Dinitroso-1,4-diazepane

1,4-Dinitroso-1,4-diazepane is a nitrosamine impurity of Nitroso carrying the CAS registry number 55557-00-1. Formula C5H10N4O2, molecular weight 158.16 g/mol. Alternative names: Dinitrosohomopiperazine and N,N-Dinitrosohomopiperazine.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

It is used as a reference standard for trace-level detection and quantitation of nitrosamine impurities by LC-MS/MS or GC-MS, supporting nitrosamine risk assessments for Nitroso, method validation (AMV) and regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer 1,4-Dinitroso-1,4-diazepane in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Nitrosamine risk assessment
Trace LC-MS/MS quantitation
Method validation (AMV)
Regulatory submissions

Industries

Related to Nitroso

View every impurity, metabolite and intermediate we list for Nitroso.

Nitroso impurities

Specifications & identifiers

Chemical identifiers
Product name	1,4-Dinitroso-1,4-diazepane
Catalogue No.	VQ-044901
CAS Number	55557-00-1
IUPAC name	1,4-dinitroso-1,4-diazepane
Molecular formula	C₅H₁₀N₄O₂
Molecular weight	158.16 g/mol
Exact mass	158.0804
Grade	Reference Standard
HSN code	38229090
InChIKey	FUCMFBXWLUGVIZ-UHFFFAOYSA-N
SMILES	C1CN(CCN(C1)N=O)N=O
PubChem CID	41473

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.5
H-bond donors / acceptors	0 / 6
TPSA	65.3 Å²

Safety & hazard information (GHS)

Toxic

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H350May cause cancer

Precautionary statements: P203, P261, P264, P264 + P265, P270, P271, P280, P301 + P316, P302 + P352, P304 + P340, P305 + P351 + P338, P318, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 1,4-Dinitroso-1,4-diazepane?

The CAS Registry Number of 1,4-Dinitroso-1,4-diazepane is 55557-00-1. It is also known as Dinitrosohomopiperazine, N,N-Dinitrosohomopiperazine, Hexahydro-1,4-dinitroso-1H-1,4-diazepine.

What is the molecular formula and molecular weight of 1,4-Dinitroso-1,4-diazepane?

1,4-Dinitroso-1,4-diazepane has the molecular formula C5H10N4O2 and a molecular weight of 158.16 g/mol. Its IUPAC name is 1,4-dinitroso-1,4-diazepane.

What is 1,4-Dinitroso-1,4-diazepane used for?

1,4-Dinitroso-1,4-diazepane is supplied as a characterised reference material related to Nitroso. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 1,4-Dinitroso-1,4-diazepane can I order?

We supply 1,4-Dinitroso-1,4-diazepane in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 1,4-Dinitroso-1,4-diazepane?

Yes. Every lot of 1,4-Dinitroso-1,4-diazepane is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 1,4-Dinitroso-1,4-diazepane be shipped internationally?

Yes. 1,4-Dinitroso-1,4-diazepane is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.