4-Chloro-1-methylpiperidine

About 4-Chloro-1-methylpiperidine

4-Chloro-1-methylpiperidine is an impurity of Ketotifen carrying the CAS registry number 5570-77-4. The compound has the formula C6H12ClN, corresponding to a molecular weight of 133.62 g/mol. Alternative names: 4-Chloro-N-methylpiperidine and N-methyl-4-chloropiperidine.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

As a characterised impurity of Ketotifen, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Ketotifen

View every impurity, metabolite and intermediate we list for Ketotifen.

Ketotifen impurities

Specifications & identifiers

Chemical identifiers
Product name	4-Chloro-1-methylpiperidine
Catalogue No.	VQ-025255
CAS Number	5570-77-4
IUPAC name	4-chloro-1-methylpiperidine
Molecular formula	C₆H₁₂ClN
Molecular weight	133.62 g/mol
Exact mass	133.0658
Grade	Reference Standard
HSN code	38229090
InChIKey	MYGXGCCFTPKWIH-UHFFFAOYSA-N
SMILES	CN1CCC(CC1)Cl
PubChem CID	79342

Physical properties
Physical form	Solid
LogP (XLogP3)	1.4
H-bond donors / acceptors	0 / 1
TPSA	3.2 Å²
Synonyms	4-Chloro-N-methylpiperidine, N-methyl-4-chloropiperidine, Piperidine, 4-chloro-1-methyl-, 4-Chloro-N-methylpiperidine hydrochloride (Salt/Mix), 1-Methyl-4-chloropiperidine hydrochloride (Salt/Mix), 1-Methyl-4-chloropiperidine, N-Methyl-4-chloro-piperidine, 1-Methyl-4-chloro-piperidine, N-methyl 4-chloropiperidine, N-Methyl-4-Chloropiperdine, 4-chloro-N-methyl-piperidine

Safety & hazard information (GHS)

Flammable

Corrosive

Toxic

Harmful / irritant

Signal word: Danger

Hazard statements

H225Highly flammable liquid and vapor
H226Flammable liquid and vapor
H302+H312Harmful if swallowed or in contact with skin
H302Harmful if swallowed
H312Harmful in contact with skin
H314Causes severe skin burns and eye damage
H331Toxic if inhaled
H412Harmful to aquatic life with long lasting effects

Precautionary statements: P210, P233, P240, P241, P242, P243, P260, P261, P264, P270, P271, P273, P280, P301 + P317, P301 + P330 + P331, P302 + P352, P302 + P361 + P354, P303 + P361 + P353, P304 + P340, P305 + P354 + P338, P316, P317, P321, P330

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-Chloro-1-methylpiperidine?

The CAS Registry Number of 4-Chloro-1-methylpiperidine is 5570-77-4. It is also known as 4-Chloro-N-methylpiperidine, N-methyl-4-chloropiperidine, Piperidine, 4-chloro-1-methyl-.

What is the molecular formula and molecular weight of 4-Chloro-1-methylpiperidine?

4-Chloro-1-methylpiperidine has the molecular formula C6H12ClN and a molecular weight of 133.62 g/mol. Its IUPAC name is 4-chloro-1-methylpiperidine.

What is 4-Chloro-1-methylpiperidine used for?

4-Chloro-1-methylpiperidine is supplied as a characterised reference material related to Ketotifen. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-Chloro-1-methylpiperidine can I order?

We supply 4-Chloro-1-methylpiperidine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-Chloro-1-methylpiperidine?

Yes. Every lot of 4-Chloro-1-methylpiperidine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-Chloro-1-methylpiperidine be shipped internationally?

Yes. 4-Chloro-1-methylpiperidine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.