Estriol EP Impurity H

Name: Estriol EP Impurity H
Brand: Vaqora Chemicals
SKU: VQ-025625

About Estriol EP Impurity H

Estriol EP Impurity H (CAS 566-76-7) is a pharmacopeial impurity of Estriol offered by Vaqora Chemicals. The compound has the formula C18H22O3, corresponding to a molecular weight of 286.4 g/mol. The IUPAC name is (8R,9S,13S,14S,16R)-3,16-dihydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one. Common synonyms include Estriol - Impurity H and 16alpha-Hydroxyestrone.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Estriol to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Estriol EP Impurity H in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Estriol

View every impurity, metabolite and intermediate we list for Estriol.

Estriol impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Estriol EP Impurity H
Catalogue No.	VQ-025625
CAS Number	566-76-7
IUPAC name	(8R,9S,13S,14S,16R)-3,16-dihydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one
Molecular formula	C₁₈H₂₂O₃
Molecular weight	286.4 g/mol
Exact mass	286.1569
Grade	Reference Standard
HSN code	38229090
InChIKey	WPOCIZJTELRQMF-QFXBJFAPSA-N
SMILES	C[C@]12CC[C@H]3[C@H]([C@@H]1C[C@H](C2=O)O)CCC4=C3C=CC(=C4)O
PubChem CID	115116

Physical properties
Physical form	Solid
LogP (XLogP3)	2.6
H-bond donors / acceptors	2 / 3
TPSA	57.5 Å²
Synonyms	Estriol - Impurity H, 16alpha-Hydroxyestrone, 16alpha-OHE1, Hydroxyestrone-16alpha, 3,16alpha-dihydroxy-1,3,5(10)-estratrien-17-one, 3,16alpha-Dihydroxyestra-1,3,5(10)-trien-17-one, Estra-1,3,5(10)-trien-17-one, 3,16-dihydroxy-, (16alpha)-, estra-1,3,5(10)-triene-3,16alpha-diol-17-one, 16alpha-OHE, 16alpha-OH Estrone, 16-alphaOHE1

Safety & hazard information (GHS)

Health hazard

Signal word: Warning

Hazard statements

H351Suspected of causing cancer

Precautionary statements: P203, P280, P318, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Estriol EP Impurity H?

The CAS Registry Number of Estriol EP Impurity H is 566-76-7. It is also known as Estriol - Impurity H, 16alpha-Hydroxyestrone, 16alpha-OHE1.

What is the molecular formula and molecular weight of Estriol EP Impurity H?

Estriol EP Impurity H has the molecular formula C18H22O3 and a molecular weight of 286.4 g/mol. Its IUPAC name is (8R,9S,13S,14S,16R)-3,16-dihydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one.

What is Estriol EP Impurity H used for?

Estriol EP Impurity H is supplied as a characterised reference material related to Estriol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Estriol EP Impurity H can I order?

We supply Estriol EP Impurity H in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Estriol EP Impurity H?

Yes. Every lot of Estriol EP Impurity H is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Estriol EP Impurity H be shipped internationally?

Yes. Estriol EP Impurity H is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.