Imatinib EP Impurity J

About Imatinib EP Impurity J

Imatinib EP Impurity J is a pharmacopeial impurity of Imatinib carrying the CAS registry number 571186-91-9. Its molecular formula is C29H31N7O2 and its molecular weight is 509.6 g/mol. Common synonyms include Imatinib Impurity J and Imatinib Mesylate - Impurity J.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Danger” with 8 hazard statements. Review the Safety Data Sheet before use.

As a characterised impurity of Imatinib, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Imatinib EP Impurity J in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Imatinib

View every impurity, metabolite and intermediate we list for Imatinib.

Imatinib impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Imatinib EP Impurity J
Catalogue No.	VQ-022829
CAS Number	571186-91-9
IUPAC name	4-[(4-methyl-4-oxidopiperazin-4-ium-1-yl)methyl]-N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide
Molecular formula	C₂₉H₃₁N₇O₂
Molecular weight	509.6 g/mol
Exact mass	509.2539
Grade	Reference Standard
HSN code	38229090
InChIKey	MSADRWGPCQTOST-UHFFFAOYSA-N
SMILES	CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CC[N+](CC3)(C)[O-])NC4=NC=CC(=N4)C5=CN=CC=C5
PubChem CID	29982268

Physical properties
Physical form	Solid
LogP (XLogP3)	3
H-bond donors / acceptors	2 / 7
TPSA	101 Å²
Synonyms	Imatinib Impurity J, Imatinib Mesylate - Impurity J, Imatinib Mesylate Impurity J, Imatinib (Piperidine)-N-oxide, Imatinib (Piperidine)-4-oxide, Imatinib (Piperazine)-4-oxide, Imatinib Piperazine N4-Oxide

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H317May cause an allergic skin reaction
H335May cause respiratory irritation
H336May cause drowsiness or dizziness
H360May damage fertility or the unborn child
H362May cause harm to breast-fed children
H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements: P203, P260, P261, P263, P264, P270, P271, P272, P280, P301 + P317, P302 + P352, P304 + P340, P318, P319, P321, P330, P332 + P317, P333 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Imatinib EP Impurity J?

The CAS Registry Number of Imatinib EP Impurity J is 571186-91-9. It is also known as Imatinib Impurity J, Imatinib Mesylate - Impurity J, Imatinib Mesylate Impurity J.

What is the molecular formula and molecular weight of Imatinib EP Impurity J?

Imatinib EP Impurity J has the molecular formula C29H31N7O2 and a molecular weight of 509.6 g/mol. Its IUPAC name is 4-[(4-methyl-4-oxidopiperazin-4-ium-1-yl)methyl]-N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide.

What is Imatinib EP Impurity J used for?

Imatinib EP Impurity J is supplied as a characterised reference material related to Imatinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Imatinib EP Impurity J can I order?

We supply Imatinib EP Impurity J in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Imatinib EP Impurity J?

Yes. Every lot of Imatinib EP Impurity J is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Imatinib EP Impurity J be shipped internationally?

Yes. Imatinib EP Impurity J is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.