Glibenclamide EP Impurity E

Name: Glibenclamide EP Impurity E
Brand: Vaqora Chemicals
SKU: VQ-022759

About Glibenclamide EP Impurity E

Glibenclamide EP Impurity E (CAS 57334-89-1) is a pharmacopeial impurity of Glyburide offered by Vaqora Chemicals. Its molecular formula is C23H27Cl2N3O5S and its molecular weight is 528.4 g/mol. Its systematic (IUPAC) name is 3,5-dichloro-N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-2-methoxybenzamide. It is also known as 3-Chloro Glyburide or Glibenclamide - Impurity E.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Glyburide to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Glyburide

View every impurity, metabolite and intermediate we list for Glyburide.

Glyburide impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Glibenclamide EP Impurity E
Catalogue No.	VQ-022759
CAS Number	57334-89-1
IUPAC name	3,5-dichloro-N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-2-methoxybenzamide
Molecular formula	C₂₃H₂₇Cl₂N₃O₅S
Molecular weight	528.4 g/mol
Exact mass	527.1048
Grade	Reference Standard
HSN code	38229090
InChIKey	AFVBBTSZLDSNJV-UHFFFAOYSA-N
SMILES	COC1=C(C=C(C=C1Cl)Cl)C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)NC3CCCCC3
PubChem CID	125358257

Physical properties
Physical form	Solid
LogP (XLogP3)	5.3
H-bond donors / acceptors	3 / 5
TPSA	122 Å²
Synonyms	3-Chloro Glyburide, Glibenclamide - Impurity E, Glyburide Impurity E, (Glyburide IMpurity), 3,5-Dichloro-N-(4-(N-(cyclohexylcarbamoyl)sulfamoyl)phenethyl)-2-methoxybenzamide, UR 623, 3-Chloro Glyburide(Glyburide Impurity), 1-cyclohexyl-3-[[4-[2-[(3,5-dichloro-2-methoxybenzoyl)amino]ethyl]phenyl]sulfonyl]urea

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Glibenclamide EP Impurity E?

The CAS Registry Number of Glibenclamide EP Impurity E is 57334-89-1. It is also known as 3-Chloro Glyburide, Glibenclamide - Impurity E, Glyburide Impurity E.

What is the molecular formula and molecular weight of Glibenclamide EP Impurity E?

Glibenclamide EP Impurity E has the molecular formula C23H27Cl2N3O5S and a molecular weight of 528.4 g/mol. Its IUPAC name is 3,5-dichloro-N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-2-methoxybenzamide.

What is Glibenclamide EP Impurity E used for?

Glibenclamide EP Impurity E is supplied as a characterised reference material related to Glyburide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Glibenclamide EP Impurity E can I order?

We supply Glibenclamide EP Impurity E in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Glibenclamide EP Impurity E?

Yes. Every lot of Glibenclamide EP Impurity E is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Glibenclamide EP Impurity E be shipped internationally?

Yes. We export Glibenclamide EP Impurity E worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.