5-Nitro-3-(trifluoromethyl)picolinonitrile

Name: 5-Nitro-3-(trifluoromethyl)picolinonitrile
Brand: Vaqora Chemicals
SKU: VQ-029173

About 5-Nitro-3-(trifluoromethyl)picolinonitrile

5-Nitro-3-(trifluoromethyl)picolinonitrile (CAS 573762-57-9) is an impurity of Apalutamide offered by Vaqora Chemicals. Its molecular formula is C7H2F3N3O2 and its molecular weight is 217.1 g/mol. Systematically, it is named 5-nitro-3-(trifluoromethyl)pyridine-2-carbonitrile. Common synonyms include 2-Cyano-5-nitro-3-(trifluoromethyl)pyridine and 2-Cyano-5-nitro-3-trifluoromethylpyridine.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Apalutamide to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 5-Nitro-3-(trifluoromethyl)picolinonitrile is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Apalutamide

View every impurity, metabolite and intermediate we list for Apalutamide.

Apalutamide impurities

Specifications & identifiers

Chemical identifiers
Product name	5-Nitro-3-(trifluoromethyl)picolinonitrile
Catalogue No.	VQ-029173
CAS Number	573762-57-9
IUPAC name	5-nitro-3-(trifluoromethyl)pyridine-2-carbonitrile
Molecular formula	C₇H₂F₃N₃O₂
Molecular weight	217.1 g/mol
Exact mass	217.0099
Grade	Reference Standard
HSN code	38229090
InChIKey	IDGUNYFTVCEPGA-UHFFFAOYSA-N
SMILES	C1=C(C=NC(=C1C(F)(F)F)C#N)[N+](=O)[O-]
PubChem CID	21874893

Physical properties
Physical form	Solid
LogP (XLogP3)	1.6
H-bond donors / acceptors	0 / 7
TPSA	82.5 Å²
Synonyms	5-Nitro-3-trifluoromethylpyridine-2-carbonitrile, 5-Nitro-3-(trifluoromethyl)-2-pyridinecarbonitrile, 5-Nitro-3-trifluoromethyl-pyridine-2-carbonitrile, 2-Pyridinecarbonitrile, 5-nitro-3-(trifluoromethyl)-, 2-Cyano-5-nitro-3-(trifluoromethyl)pyridine, 2-Cyano-5-nitro-3-trifluoromethylpyridine, 2-cyano-3-(trifluoromethyl)-5-nitropyridine, 5-nitro-3-((trifluoromethyl))-pyridin-2-carbonitrile

Safety & hazard information (GHS)

Flammable

Signal word: Warning

Hazard statements

H228Flammable solid
H252Self-heating in large quantities, may catch fire

Precautionary statements: P210, P235, P240, P241, P280, P370 + P378, P407, P410, P413, P420

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 5-Nitro-3-(trifluoromethyl)picolinonitrile?

The CAS Registry Number of 5-Nitro-3-(trifluoromethyl)picolinonitrile is 573762-57-9. It is also known as 5-Nitro-3-trifluoromethylpyridine-2-carbonitrile, 5-Nitro-3-(trifluoromethyl)-2-pyridinecarbonitrile, 5-Nitro-3-trifluoromethyl-pyridine-2-carbonitrile.

What is the molecular formula and molecular weight of 5-Nitro-3-(trifluoromethyl)picolinonitrile?

5-Nitro-3-(trifluoromethyl)picolinonitrile has the molecular formula C7H2F3N3O2 and a molecular weight of 217.1 g/mol. Its IUPAC name is 5-nitro-3-(trifluoromethyl)pyridine-2-carbonitrile.

What is 5-Nitro-3-(trifluoromethyl)picolinonitrile used for?

5-Nitro-3-(trifluoromethyl)picolinonitrile is supplied as a characterised reference material related to Apalutamide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 5-Nitro-3-(trifluoromethyl)picolinonitrile can I order?

We supply 5-Nitro-3-(trifluoromethyl)picolinonitrile in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 5-Nitro-3-(trifluoromethyl)picolinonitrile?

Yes. Every lot of 5-Nitro-3-(trifluoromethyl)picolinonitrile is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 5-Nitro-3-(trifluoromethyl)picolinonitrile be shipped internationally?

Yes. 5-Nitro-3-(trifluoromethyl)picolinonitrile is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.