5-Amino-3-(trifluoromethyl)picolinonitrile

Name: 5-Amino-3-(trifluoromethyl)picolinonitrile
Brand: Vaqora Chemicals
SKU: VQ-024310

About 5-Amino-3-(trifluoromethyl)picolinonitrile

Vaqora Chemicals supplies 5-Amino-3-(trifluoromethyl)picolinonitrile, an impurity of Apalutamide registered under CAS number 573762-62-6. Its molecular formula is C7H4F3N3 and its molecular weight is 187.12 g/mol. Its systematic (IUPAC) name is 5-amino-3-(trifluoromethyl)pyridine-2-carbonitrile. Alternative names: 5-Amino-2-cyano-3-trifluoromethylpyridine and 2-cyano-3-(trifluoromethyl)-5-aminopyridine.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Apalutamide to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer 5-Amino-3-(trifluoromethyl)picolinonitrile in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Apalutamide

View every impurity, metabolite and intermediate we list for Apalutamide.

Apalutamide impurities

Specifications & identifiers

Chemical identifiers
Product name	5-Amino-3-(trifluoromethyl)picolinonitrile
Catalogue No.	VQ-024310
CAS Number	573762-62-6
IUPAC name	5-amino-3-(trifluoromethyl)pyridine-2-carbonitrile
Molecular formula	C₇H₄F₃N₃
Molecular weight	187.12 g/mol
Exact mass	187.0357
Grade	Reference Standard
HSN code	38229090
InChIKey	WLMSCOVORZUSNW-UHFFFAOYSA-N
SMILES	C1=C(C=NC(=C1C(F)(F)F)C#N)N
PubChem CID	13532246

Physical properties
Physical form	Solid
LogP (XLogP3)	1.1
H-bond donors / acceptors	1 / 6
TPSA	62.7 Å²
Synonyms	5-Amino-3-(trifluoromethyl)-2-pyridinecarbonitrile, 5-Amino-2-cyano-3-trifluoromethylpyridine, 2-cyano-3-(trifluoromethyl)-5-aminopyridine, 2-cyano-3-trifluoromethyl-5-(amino)pyridine, 2-Pyridinecarbonitrile, 5-amino-3-(trifluoromethyl)-

Safety & hazard information (GHS)

Toxic

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H412Harmful to aquatic life with long lasting effects

Precautionary statements: P264, P270, P273, P301 + P316, P321, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 5-Amino-3-(trifluoromethyl)picolinonitrile?

The CAS Registry Number of 5-Amino-3-(trifluoromethyl)picolinonitrile is 573762-62-6. It is also known as 5-Amino-3-(trifluoromethyl)-2-pyridinecarbonitrile, 5-Amino-2-cyano-3-trifluoromethylpyridine, 2-cyano-3-(trifluoromethyl)-5-aminopyridine.

What is the molecular formula and molecular weight of 5-Amino-3-(trifluoromethyl)picolinonitrile?

5-Amino-3-(trifluoromethyl)picolinonitrile has the molecular formula C7H4F3N3 and a molecular weight of 187.12 g/mol. Its IUPAC name is 5-amino-3-(trifluoromethyl)pyridine-2-carbonitrile.

What is 5-Amino-3-(trifluoromethyl)picolinonitrile used for?

5-Amino-3-(trifluoromethyl)picolinonitrile is supplied as a characterised reference material related to Apalutamide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 5-Amino-3-(trifluoromethyl)picolinonitrile can I order?

We supply 5-Amino-3-(trifluoromethyl)picolinonitrile in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 5-Amino-3-(trifluoromethyl)picolinonitrile?

Yes. Every lot of 5-Amino-3-(trifluoromethyl)picolinonitrile is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 5-Amino-3-(trifluoromethyl)picolinonitrile be shipped internationally?

Yes. 5-Amino-3-(trifluoromethyl)picolinonitrile is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.