(R,S)-Nornicotine

Name: (R,S)-Nornicotine
Brand: Vaqora Chemicals
SKU: VQ-032139

About (R,S)-Nornicotine

Vaqora Chemicals supplies (R,S)-Nornicotine, an impurity of Nicotine registered under CAS number 5746-86-1. The compound has the formula C9H12N2, corresponding to a molecular weight of 148.2 g/mol. The IUPAC name is 3-pyrrolidin-2-ylpyridine. Common synonyms include 3-(Pyrrolidin-2-yl)pyridine and Nornicotine Racemate.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Nicotine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, (R,S)-Nornicotine is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Nicotine

View every impurity, metabolite and intermediate we list for Nicotine.

Nicotine impurities

Specifications & identifiers

Chemical identifiers
Product name	(R,S)-Nornicotine
Catalogue No.	VQ-032139
CAS Number	5746-86-1
IUPAC name	3-pyrrolidin-2-ylpyridine
Molecular formula	C₉H₁₂N₂
Molecular weight	148.2 g/mol
Exact mass	148.1
Grade	Reference Standard
HSN code	38229090
InChIKey	MYKUKUCHPMASKF-UHFFFAOYSA-N
SMILES	C1CC(NC1)C2=CN=CC=C2
PubChem CID	412

Physical properties
Physical form	Solid
LogP (XLogP3)	0.2
H-bond donors / acceptors	1 / 2
TPSA	24.9 Å²
Synonyms	3-(Pyrrolidin-2-yl)pyridine, Nornicotine Racemate, 3-pyrrolidin-2-yl-pyridine, (+-)-Nornicotine, (+/-)-Nornicotine, (+-)-1'-Demethylnicotine, dl-Norcitine, ( inverted exclamation markA)-Nornicotine, 3-(2-Pyrrolidyl)pyridine, (+-)-3-(2-Pyrrolidinyl)pyridine, (S)-3-Pyrrolidin-2-yl-pyridine

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (R,S)-Nornicotine?

The CAS Registry Number of (R,S)-Nornicotine is 5746-86-1. It is also known as 3-(Pyrrolidin-2-yl)pyridine, Nornicotine Racemate, 3-pyrrolidin-2-yl-pyridine.

What is the molecular formula and molecular weight of (R,S)-Nornicotine?

(R,S)-Nornicotine has the molecular formula C9H12N2 and a molecular weight of 148.2 g/mol. Its IUPAC name is 3-pyrrolidin-2-ylpyridine.

What is (R,S)-Nornicotine used for?

(R,S)-Nornicotine is supplied as a characterised reference material related to Nicotine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (R,S)-Nornicotine can I order?

We supply (R,S)-Nornicotine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (R,S)-Nornicotine?

Yes. Every lot of (R,S)-Nornicotine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (R,S)-Nornicotine be shipped internationally?

Yes. (R,S)-Nornicotine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.