8-Chloroquinolin-4-ol

Name: 8-Chloroquinolin-4-ol
Brand: Vaqora Chemicals
SKU: VQ-052033

About 8-Chloroquinolin-4-ol

8-Chloroquinolin-4-ol is a process intermediate or related compound of Hydroxychloroquine carrying the CAS registry number 57797-97-4. With the molecular formula C9H6ClNO, it has a molar mass of 179.6 g/mol. Its systematic (IUPAC) name is 8-chloro-1H-quinolin-4-one. Alternative names: 8-Chloro-4-hydroxyquinoline and 8-Chloro-4-quinolinol.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

It is a process intermediate or related compound in the synthesis of Hydroxychloroquine, useful for route development, impurity fate-and-purge studies and analytical method development. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 8-Chloroquinolin-4-ol in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Hydroxychloroquine

View every impurity, metabolite and intermediate we list for Hydroxychloroquine.

Hydroxychloroquine impurities

Specifications & identifiers

Chemical identifiers
Product name	8-Chloroquinolin-4-ol
Catalogue No.	VQ-052033
CAS Number	57797-97-4
IUPAC name	8-chloro-1H-quinolin-4-one
Molecular formula	C₉H₆ClNO
Molecular weight	179.6 g/mol
Exact mass	179.0138
HSN code	2933
InChIKey	SUZPLFOSYVTCLE-UHFFFAOYSA-N
SMILES	C1=CC2=C(C(=C1)Cl)NC=CC2=O
PubChem CID	265885

Physical properties
Physical form	Solid
LogP (XLogP3)	2.2
H-bond donors / acceptors	1 / 2
TPSA	29.1 Å²
Synonyms	8-Chloro-4-hydroxyquinoline, 8-Chloro-4-quinolinol, 4-Quinolinol, 8-chloro-, 8-chloroquinolin-4(1H)-one, 8-chlorohydroquinolin-4-one, 4-Hydroxy-8-chloroquinoline, 8-chloro-4(1H)-Quinolinone, 4-Chloro-4-hydroxyquinoline, 8-chloranyl-1H-quinolin-4-one, 8-Chloro-4-hydroxyquinoline, AldrichCPR

Safety & hazard information (GHS)

Corrosive

Toxic

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H318Causes serious eye damage

Precautionary statements: P264, P264 + P265, P270, P280, P301 + P316, P305 + P354 + P338, P317, P321, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 8-Chloroquinolin-4-ol?

The CAS Registry Number of 8-Chloroquinolin-4-ol is 57797-97-4. It is also known as 8-Chloro-4-hydroxyquinoline, 8-Chloro-4-quinolinol, 4-Quinolinol, 8-chloro-.

What is the molecular formula and molecular weight of 8-Chloroquinolin-4-ol?

8-Chloroquinolin-4-ol has the molecular formula C9H6ClNO and a molecular weight of 179.6 g/mol. Its IUPAC name is 8-chloro-1H-quinolin-4-one.

What is 8-Chloroquinolin-4-ol used for?

8-Chloroquinolin-4-ol is supplied as a characterised reference material related to Hydroxychloroquine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 8-Chloroquinolin-4-ol can I order?

We supply 8-Chloroquinolin-4-ol, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 8-Chloroquinolin-4-ol?

Yes. Every lot of 8-Chloroquinolin-4-ol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 8-Chloroquinolin-4-ol be shipped internationally?

Yes. 8-Chloroquinolin-4-ol is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.