Dextromethorphan EP Impurity C

About Dextromethorphan EP Impurity C

Dextromethorphan EP Impurity C is a pharmacopeial impurity of Dextromethorphan carrying the CAS registry number 57969-05-8. With the molecular formula C18H23NO2, it has a molar mass of 285.4 g/mol. Systematically, it is named (1S,9R,10S)-4-methoxy-17-methyl-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-8-one. It is also known as ent-3-Methoxy-17-methylmorphinan-10-one or 10-Keto dextromethorphan.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As a characterised impurity of Dextromethorphan, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Dextromethorphan EP Impurity C is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Dextromethorphan

View every impurity, metabolite and intermediate we list for Dextromethorphan.

Dextromethorphan impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Dextromethorphan EP Impurity C
Catalogue No.	VQ-006327
CAS Number	57969-05-8
IUPAC name	(1S,9R,10S)-4-methoxy-17-methyl-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-8-one
Molecular formula	C₁₈H₂₃NO₂
Molecular weight	285.4 g/mol
Exact mass	285.1729
Grade	Reference Standard
HSN code	38229090
InChIKey	UOCRGKKCNCIQCZ-KYJSFNMBSA-N
SMILES	CN1CC[C@@]23CCCC[C@@H]2[C@@H]1C(=O)C4=C3C=C(C=C4)OC
PubChem CID	21780010

Physical properties
Physical form	Solid
LogP (XLogP3)	3.8
H-bond donors / acceptors	0 / 3
TPSA	29.5 Å²
Synonyms	(9a,13a,14a)-3-Methoxy-17-methylmorphinan-10-one, ent-3-Methoxy-17-methylmorphinan-10-one, (9alpha,13alpha,14alpha)-3-Methoxy-17-methylmorphinan-10-one, 10-Keto dextromethorphan, Dextromethorphan Related Compound C (USP), 3-Methoxy-17-methylmorphinan-10-one, ent-, Morphinan-10-one, 3-methoxy-17-methyl-, (9alpha,13alpha,14alpha)-, Dextromethorphan hydrobromide impurity C, Dextromethorphan hydrobromide specified impurity C, 10-Keto Dextromethorphan (1.0mg/ml in Acetonitrile), 10-Keto Dextromethorphan (1 mg/ml in Acetonitrile), ent-3-Methoxy-17-methylmorphinan-10-one (10-Ketodextromethorphan)

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Dextromethorphan EP Impurity C?

The CAS Registry Number of Dextromethorphan EP Impurity C is 57969-05-8. It is also known as (9a,13a,14a)-3-Methoxy-17-methylmorphinan-10-one, ent-3-Methoxy-17-methylmorphinan-10-one, (9alpha,13alpha,14alpha)-3-Methoxy-17-methylmorphinan-10-one.

What is the molecular formula and molecular weight of Dextromethorphan EP Impurity C?

Dextromethorphan EP Impurity C has the molecular formula C18H23NO2 and a molecular weight of 285.4 g/mol. Its IUPAC name is (1S,9R,10S)-4-methoxy-17-methyl-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-8-one.

What is Dextromethorphan EP Impurity C used for?

Dextromethorphan EP Impurity C is supplied as a characterised reference material related to Dextromethorphan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Dextromethorphan EP Impurity C can I order?

We supply Dextromethorphan EP Impurity C in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Dextromethorphan EP Impurity C?

Yes. Every lot of Dextromethorphan EP Impurity C is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Dextromethorphan EP Impurity C be shipped internationally?

Yes. Dextromethorphan EP Impurity C is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.