2,5-Di-tert-butylphenol

About 2,5-Di-tert-butylphenol

2,5-Di-tert-butylphenol is an API impurity reference standard carrying the CAS registry number 5875-45-6. With the molecular formula C14H22O, it has a molar mass of 206.32 g/mol. Common synonyms include 2,5-bis(1,1-dimethylethyl)-Phenol and 2,5-bis(1,1-Dimethylethyl)phenol.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of the parent drug substance to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 2,5-Di-tert-butylphenol is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Specifications & identifiers

Chemical identifiers
Product name	2,5-Di-tert-butylphenol
Catalogue No.	VQ-032845
CAS Number	5875-45-6
IUPAC name	2,5-ditert-butylphenol
Molecular formula	C₁₄H₂₂O
Molecular weight	206.32 g/mol
Exact mass	206.1671
Grade	Reference Standard
HSN code	38229090
InChIKey	KDBZVULQVCUNNA-UHFFFAOYSA-N
SMILES	CC(C)(C)C1=CC(=C(C=C1)C(C)(C)C)O
PubChem CID	79983

Physical properties
Physical form	Solid
LogP (XLogP3)	4.9
H-bond donors / acceptors	1 / 1
TPSA	20.2 Å²
Synonyms	2,5-bis(1,1-dimethylethyl)-Phenol, 2,5-bis(1,1-Dimethylethyl)phenol, Phenol, 2,5-bis(1,1-dimethylethyl)-, Phenol, 2,5-di-tert-butyl-, 3,6-di-tert-butylphenol, Phenol, 2,5-di-tert-butyl-(8CI), 2,5-di-t-butylphenol, 2,5-di-t-butyl phenol, 2,5-bis(tert-butyl)phenol

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H413May cause long lasting harmful effects to aquatic life

Precautionary statements: P261, P264, P264 + P265, P271, P273, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2,5-Di-tert-butylphenol?

The CAS Registry Number of 2,5-Di-tert-butylphenol is 5875-45-6. It is also known as 2,5-bis(1,1-dimethylethyl)-Phenol, 2,5-bis(1,1-Dimethylethyl)phenol, Phenol, 2,5-bis(1,1-dimethylethyl)-.

What is the molecular formula and molecular weight of 2,5-Di-tert-butylphenol?

2,5-Di-tert-butylphenol has the molecular formula C14H22O and a molecular weight of 206.32 g/mol. Its IUPAC name is 2,5-ditert-butylphenol.

Which grade and pack sizes of 2,5-Di-tert-butylphenol can I order?

We supply 2,5-Di-tert-butylphenol in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2,5-Di-tert-butylphenol?

Yes. Every lot of 2,5-Di-tert-butylphenol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2,5-Di-tert-butylphenol be shipped internationally?

Yes. 2,5-Di-tert-butylphenol is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.