N,N-Diethylnicotinamide (Nikethamide)

About N,N-Diethylnicotinamide (Nikethamide)

N,N-Diethylnicotinamide (Nikethamide) is an impurity of Nicotinamide carrying the CAS registry number 59-26-7. Formula C10H14N2O, molecular weight 178.23 g/mol. Its systematic (IUPAC) name is N,N-diethylpyridine-3-carboxamide. It is also known as Nikethamide or N,N-Diethylnicotinamide.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

This Nicotinamide impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer N,N-Diethylnicotinamide (Nikethamide) in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Nicotinamide

View every impurity, metabolite and intermediate we list for Nicotinamide.

Nicotinamide impurities

Specifications & identifiers

Chemical identifiers
Product name	N,N-Diethylnicotinamide (Nikethamide)
Catalogue No.	VQ-032527
CAS Number	59-26-7
IUPAC name	N,N-diethylpyridine-3-carboxamide
Molecular formula	C₁₀H₁₄N₂O
Molecular weight	178.23 g/mol
Exact mass	178.1106
Grade	Reference Standard
HSN code	38229090
InChIKey	NCYVXEGFNDZQCU-UHFFFAOYSA-N
SMILES	CCN(CC)C(=O)C1=CN=CC=C1
PubChem CID	5497

Physical properties
Physical form	Solid
LogP (XLogP3)	0.3
H-bond donors / acceptors	0 / 2
TPSA	33.2 Å²
Synonyms	Nikethamide, N,N-Diethylnicotinamide, Nicethamide, Nikethyl, Carditonic, Diaethylamidum acidi nicotinici, Nicotinic Diethylamide, Diethylamide, Nicotinic, Anacardone, Coramine, 3-Pyridinecarboxamide, N,N-diethyl-

Safety & hazard information (GHS)

Toxic

Harmful / irritant

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P316, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N,N-Diethylnicotinamide (Nikethamide)?

The CAS Registry Number of N,N-Diethylnicotinamide (Nikethamide) is 59-26-7. It is also known as Nikethamide, N,N-Diethylnicotinamide, Nicethamide.

What is the molecular formula and molecular weight of N,N-Diethylnicotinamide (Nikethamide)?

N,N-Diethylnicotinamide (Nikethamide) has the molecular formula C10H14N2O and a molecular weight of 178.23 g/mol. Its IUPAC name is N,N-diethylpyridine-3-carboxamide.

What is N,N-Diethylnicotinamide (Nikethamide) used for?

N,N-Diethylnicotinamide (Nikethamide) is supplied as a characterised reference material related to Nicotinamide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N,N-Diethylnicotinamide (Nikethamide) can I order?

We supply N,N-Diethylnicotinamide (Nikethamide) in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N,N-Diethylnicotinamide (Nikethamide)?

Yes. Every lot of N,N-Diethylnicotinamide (Nikethamide) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N,N-Diethylnicotinamide (Nikethamide) be shipped internationally?

Yes. N,N-Diethylnicotinamide (Nikethamide) is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.