Diethyl 4-hydroxyisophthalate

About Diethyl 4-hydroxyisophthalate

Diethyl 4-hydroxyisophthalate is a metabolite or degradation product of Teriflunomide carrying the CAS registry number 5985-25-1. Formula C12H14O5, molecular weight 238.24 g/mol. Its systematic (IUPAC) name is diethyl 4-hydroxybenzene-1,3-dicarboxylate. Common synonyms include Isophthalic acid, 4-hydroxy-, diethyl ester and 4-Hydroxyisophthalic acid, diethyl ester.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

Analytical teams use this compound to identify metabolites and degradants of Teriflunomide, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Diethyl 4-hydroxyisophthalate in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling
Fine chemical synthesis

Industries

Related to Teriflunomide

View every impurity, metabolite and intermediate we list for Teriflunomide.

Teriflunomide impurities

Specifications & identifiers

Chemical identifiers
Product name	Diethyl 4-hydroxyisophthalate
Catalogue No.	VQ-031836
CAS Number	5985-25-1
IUPAC name	diethyl 4-hydroxybenzene-1,3-dicarboxylate
Molecular formula	C₁₂H₁₄O₅
Molecular weight	238.24 g/mol
Exact mass	238.0841
Grade	Reference Standard
HSN code	38229090
InChIKey	BPSXYFMGSNKFDZ-UHFFFAOYSA-N
SMILES	CCOC(=O)C1=CC(=C(C=C1)O)C(=O)OCC
PubChem CID	256772

Physical properties
Physical form	Solid
LogP (XLogP3)	3.2
H-bond donors / acceptors	1 / 5
TPSA	72.8 Å²
Synonyms	Isophthalic acid, 4-hydroxy-, diethyl ester, 1,3-Benzenedicarboxylic acid, 4-hydroxy-, diethyl ester, 1,3-Benzenedicarboxylic acid, 4-hydroxy-, 1,3-diethyl ester, 4-Hydroxyisophthalic acid, diethyl ester, 1, 4-hydroxy-, diethyl ester

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Diethyl 4-hydroxyisophthalate?

The CAS Registry Number of Diethyl 4-hydroxyisophthalate is 5985-25-1. It is also known as Isophthalic acid, 4-hydroxy-, diethyl ester, 1,3-Benzenedicarboxylic acid, 4-hydroxy-, diethyl ester, 1,3-Benzenedicarboxylic acid, 4-hydroxy-, 1,3-diethyl ester.

What is the molecular formula and molecular weight of Diethyl 4-hydroxyisophthalate?

Diethyl 4-hydroxyisophthalate has the molecular formula C12H14O5 and a molecular weight of 238.24 g/mol. Its IUPAC name is diethyl 4-hydroxybenzene-1,3-dicarboxylate.

What is Diethyl 4-hydroxyisophthalate used for?

Diethyl 4-hydroxyisophthalate is supplied as a characterised reference material related to Teriflunomide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Diethyl 4-hydroxyisophthalate can I order?

We supply Diethyl 4-hydroxyisophthalate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Diethyl 4-hydroxyisophthalate?

Yes. Every lot of Diethyl 4-hydroxyisophthalate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Diethyl 4-hydroxyisophthalate be shipped internationally?

Yes. We export Diethyl 4-hydroxyisophthalate worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.