Ibuprofen EP Impurity M

About Ibuprofen EP Impurity M

Ibuprofen EP Impurity M is a pharmacopeial impurity of Ibuprofen carrying the CAS registry number 60057-62-7. Formula C13H18O3, molecular weight 222.28 g/mol. Systematically, it is named 2-hydroxy-2-[4-(2-methylpropyl)phenyl]propanoic acid. Common synonyms include rac a-Hydroxy Ibuprofen and Ibuprofen - Impurity M.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 2 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Ibuprofen to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Ibuprofen EP Impurity M is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Ibuprofen

View every impurity, metabolite and intermediate we list for Ibuprofen.

Ibuprofen impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Ibuprofen EP Impurity M
Catalogue No.	VQ-026108
CAS Number	60057-62-7
IUPAC name	2-hydroxy-2-[4-(2-methylpropyl)phenyl]propanoic acid
Molecular formula	C₁₃H₁₈O₃
Molecular weight	222.28 g/mol
Exact mass	222.1256
Grade	Reference Standard
HSN code	38229090
InChIKey	APEODKDQAWQDLW-UHFFFAOYSA-N
SMILES	CC(C)CC1=CC=C(C=C1)C(C)(C(=O)O)O
PubChem CID	5228577

Physical properties
Physical form	Solid
LogP (XLogP3)	2.8
H-bond donors / acceptors	2 / 3
TPSA	57.5 Å²
Synonyms	rac a-Hydroxy Ibuprofen, Ibuprofen - Impurity M, rac alpha-Hydroxy Ibuprofen, 2-(4-Isobutylphenyl)-2-hydroxypropionic Acid, 2-(p-Isobutylphenyl)lactic Acid, 2-Hydroxy-2-(4-isobutylphenyl)propionic Acid, 2-(p-Isobutylphenyl)-2-hydroxypropionic acid, (2RS)-2-Hydroxy-2-(4-(2-methylpropyl)phenyl)propanoic acid, Benzeneacetic acid, alpha-hydroxy-alpha-methyl-4-(2-methylpropyl)-, (2RS)-2-Hydroxy-2-[4-(2-methylpropyl)phenyl]propanoic Acid, Ibuprofen Impurity M, 2-hydroxy-2-(4-isobutylphenyl)propanoic acid

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H319Causes serious eye irritation

Precautionary statements: P264, P264 + P265, P270, P280, P301 + P317, P305 + P351 + P338, P330, P337 + P317, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ibuprofen EP Impurity M?

The CAS Registry Number of Ibuprofen EP Impurity M is 60057-62-7. It is also known as rac a-Hydroxy Ibuprofen, Ibuprofen - Impurity M, rac alpha-Hydroxy Ibuprofen.

What is the molecular formula and molecular weight of Ibuprofen EP Impurity M?

Ibuprofen EP Impurity M has the molecular formula C13H18O3 and a molecular weight of 222.28 g/mol. Its IUPAC name is 2-hydroxy-2-[4-(2-methylpropyl)phenyl]propanoic acid.

What is Ibuprofen EP Impurity M used for?

Ibuprofen EP Impurity M is supplied as a characterised reference material related to Ibuprofen. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ibuprofen EP Impurity M can I order?

We supply Ibuprofen EP Impurity M in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ibuprofen EP Impurity M?

Yes. Every lot of Ibuprofen EP Impurity M is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ibuprofen EP Impurity M be shipped internationally?

Yes. Ibuprofen EP Impurity M is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.