Protopine Hydrochloride

Name: Protopine Hydrochloride
Brand: Vaqora Chemicals
SKU: VQ-051518

About Protopine Hydrochloride

Listed under CAS 6164-47-2, Protopine Hydrochloride is a process intermediate or related compound of Allopurinol available from Vaqora Chemicals. Formula C20H20ClNO5, molecular weight 389.8 g/mol. Common synonyms include Protopine HCl.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Danger” with 1 hazard statement. Review the Safety Data Sheet before use.

It is a process intermediate or related compound in the synthesis of Allopurinol, useful for route development, impurity fate-and-purge studies and analytical method development. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Protopine Hydrochloride in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Allopurinol

View every impurity, metabolite and intermediate we list for Allopurinol.

Allopurinol impurities

Specifications & identifiers

Chemical identifiers
Product name	Protopine Hydrochloride
Catalogue No.	VQ-051518
CAS Number	6164-47-2
IUPAC name	15-methyl-7,9,19,21-tetraoxa-15-azapentacyclo[15.7.0.04,12.06,10.018,22]tetracosa-1(17),4,6(10),11,18(22),23-hexaen-3-one;hydrochloride
Molecular formula	C₂₀H₂₀ClNO₅
Molecular weight	389.8 g/mol
Exact mass	389.103
HSN code	2933
InChIKey	NWNVDSJZGYDVQW-UHFFFAOYSA-N
SMILES	CN1CCC2=CC3=C(C=C2C(=O)CC4=C(C1)C5=C(C=C4)OCO5)OCO3.Cl
PubChem CID	22543

Physical properties
Physical form	Solid
H-bond donors / acceptors	1 / 6
TPSA	57.2 Å²

Safety & hazard information (GHS)

Toxic

Signal word: Danger

Hazard statements

H301Toxic if swallowed

Precautionary statements: P264, P270, P301 + P316, P321, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Protopine Hydrochloride?

The CAS Registry Number of Protopine Hydrochloride is 6164-47-2. It is also known as Protopine HCl, 7,13a-Secoberbin-13a-one, 7-methyl-2,3:9,10-bis(methylenedioxy)-, hydrochloride, 7, 7-methyl-2,3:9,10-bis(methylenedioxy)-, hydrochloride.

What is the molecular formula and molecular weight of Protopine Hydrochloride?

Protopine Hydrochloride has the molecular formula C20H20ClNO5 and a molecular weight of 389.8 g/mol.

What is Protopine Hydrochloride used for?

Protopine Hydrochloride is supplied as a characterised reference material related to Allopurinol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Protopine Hydrochloride can I order?

We supply Protopine Hydrochloride, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Protopine Hydrochloride?

Yes. Every lot of Protopine Hydrochloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Protopine Hydrochloride be shipped internationally?

Yes. Protopine Hydrochloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.