Amitriptyline EP Impurity B

Name: Amitriptyline EP Impurity B
Brand: Vaqora Chemicals
SKU: VQ-025106

About Amitriptyline EP Impurity B

Amitriptyline EP Impurity B (CAS 6202-23-9) is a pharmacopeial impurity of Cyclobenzaprine offered by Vaqora Chemicals. With the molecular formula C20H22ClN, it has a molar mass of 311.8 g/mol. Alternative names: Cyclobenzaprine Hydrochloride and Nortriptyline EP Impurity E Hydrochloride.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

This Cyclobenzaprine impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Amitriptyline EP Impurity B in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Cyclobenzaprine

View every impurity, metabolite and intermediate we list for Cyclobenzaprine.

Cyclobenzaprine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Amitriptyline EP Impurity B
Catalogue No.	VQ-025106
CAS Number	6202-23-9
IUPAC name	N,N-dimethyl-3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,9,11,13-heptaenylidene)propan-1-amine;hydrochloride
Molecular formula	C₂₀H₂₂ClN
Molecular weight	311.8 g/mol
Exact mass	311.1441
Grade	Reference Standard
HSN code	38229090
InChIKey	VXEAYBOGHINOKW-UHFFFAOYSA-N
SMILES	CN(C)CCC=C1C2=CC=CC=C2C=CC3=CC=CC=C31.Cl
PubChem CID	22576

Physical properties
Physical form	Solid
H-bond donors / acceptors	1 / 1
TPSA	3.2 Å²
Synonyms	Cyclobenzaprine Hydrochloride, Nortriptyline EP Impurity E Hydrochloride, Amitriptyline EP Impurity B (HCl salt), Amitriptyline Hydrochloride - Impurity B, Nortriptyline Hydrochloride - Impurity E, Amitriptyline Impurity B, Cyclobenzaprine HCL, Novo-Cycloprine, Tabradol, TNX-102, 10,11delta-Amitriptyline hydrochloride, 3-(5H-Dibenzo(a,d)cyclohepten-5-ylidene)propyl(dimethyl)ammonium chloride

Safety & hazard information (GHS)

Toxic

Harmful / irritant

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H312Harmful in contact with skin
H317May cause an allergic skin reaction
H332Harmful if inhaled

Precautionary statements: P261, P264, P270, P271, P272, P280, P301 + P316, P302 + P352, P304 + P340, P317, P321, P330, P333 + P317, P362 + P364, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Amitriptyline EP Impurity B?

The CAS Registry Number of Amitriptyline EP Impurity B is 6202-23-9. It is also known as Cyclobenzaprine Hydrochloride, Nortriptyline EP Impurity E Hydrochloride, Amitriptyline EP Impurity B (HCl salt).

What is the molecular formula and molecular weight of Amitriptyline EP Impurity B?

Amitriptyline EP Impurity B has the molecular formula C20H22ClN and a molecular weight of 311.8 g/mol.

What is Amitriptyline EP Impurity B used for?

Amitriptyline EP Impurity B is supplied as a characterised reference material related to Cyclobenzaprine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Amitriptyline EP Impurity B can I order?

We supply Amitriptyline EP Impurity B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Amitriptyline EP Impurity B?

Yes. Every lot of Amitriptyline EP Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Amitriptyline EP Impurity B be shipped internationally?

Yes. Amitriptyline EP Impurity B is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.