4-Iodo-D-phenylalanine

Name: 4-Iodo-D-phenylalanine
Brand: Vaqora Chemicals
SKU: VQ-027291

About 4-Iodo-D-phenylalanine

4-Iodo-D-phenylalanine (CAS 62561-75-5) is an impurity of Sacubitril offered by Vaqora Chemicals. With the molecular formula C9H10INO2, it has a molar mass of 291.09 g/mol. Its systematic (IUPAC) name is (2R)-2-amino-3-(4-iodophenyl)propanoic acid. Common synonyms include D-p-Iodophenylalanine and para-iodo-d-phenylalanine.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Warning” with 3 hazard statements. Review the Safety Data Sheet before use.

This Sacubitril impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer 4-Iodo-D-phenylalanine in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Sacubitril

View every impurity, metabolite and intermediate we list for Sacubitril.

Sacubitril impurities

Specifications & identifiers

Chemical identifiers
Product name	4-Iodo-D-phenylalanine
Catalogue No.	VQ-027291
CAS Number	62561-75-5
IUPAC name	(2R)-2-amino-3-(4-iodophenyl)propanoic acid
Molecular formula	C₉H₁₀INO₂
Molecular weight	291.09 g/mol
Exact mass	290.9756
Grade	Reference Standard
HSN code	38229090
InChIKey	PZNQZSRPDOEBMS-MRVPVSSYSA-N
SMILES	C1=CC(=CC=C1C[C@H](C(=O)O)N)I
PubChem CID	2733279

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.9
H-bond donors / acceptors	2 / 3
TPSA	63.3 Å²
Synonyms	D-p-Iodophenylalanine, para-iodo-d-phenylalanine, h-d-phe(4-i)-oh, D-4-Iodophenylalanine, d-4-iodophe, D-Phenylalanine, 4-iodo-, (R)-2-amino-3-(4-iodophenyl)propanoic acid, h-p-iodo-d-phe-oh, (d)-4-iodophenyl alanine, (2R)-2-azaniumyl-3-(4-bromophenyl)propanoate, d-phe(4-i)-oh, d-4-iodo phenylalanine

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-Iodo-D-phenylalanine?

The CAS Registry Number of 4-Iodo-D-phenylalanine is 62561-75-5. It is also known as D-p-Iodophenylalanine, para-iodo-d-phenylalanine, h-d-phe(4-i)-oh.

What is the molecular formula and molecular weight of 4-Iodo-D-phenylalanine?

4-Iodo-D-phenylalanine has the molecular formula C9H10INO2 and a molecular weight of 291.09 g/mol. Its IUPAC name is (2R)-2-amino-3-(4-iodophenyl)propanoic acid.

What is 4-Iodo-D-phenylalanine used for?

4-Iodo-D-phenylalanine is supplied as a characterised reference material related to Sacubitril. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-Iodo-D-phenylalanine can I order?

We supply 4-Iodo-D-phenylalanine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-Iodo-D-phenylalanine?

Yes. Every lot of 4-Iodo-D-phenylalanine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-Iodo-D-phenylalanine be shipped internationally?

Yes. 4-Iodo-D-phenylalanine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.