Ethyl 3-aminocrotonate

About Ethyl 3-aminocrotonate

Ethyl 3-aminocrotonate is an impurity of Allopurinol carrying the CAS registry number 626-34-6. With the molecular formula C6H11NO2, it has a molar mass of 129.16 g/mol. Systematically, it is named ethyl (E)-3-aminobut-2-enoate. It is also known as (Z)-Ethyl 3-Aminocrotonate or (Z)-Ethyl 3-aminobut-2-enoate.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

This Allopurinol impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Ethyl 3-aminocrotonate is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Allopurinol

View every impurity, metabolite and intermediate we list for Allopurinol.

Allopurinol impurities

Specifications & identifiers

Chemical identifiers
Product name	Ethyl 3-aminocrotonate
Catalogue No.	VQ-032656
CAS Number	626-34-6
IUPAC name	ethyl (E)-3-aminobut-2-enoate
Molecular formula	C₆H₁₁NO₂
Molecular weight	129.16 g/mol
Exact mass	129.079
Grade	Reference Standard
HSN code	38229090
InChIKey	YPMPTULBFPFSEQ-SNAWJCMRSA-N
SMILES	CCOC(=O)/C=C(\C)/N
PubChem CID	637551

Physical properties
Physical form	Solid
LogP (XLogP3)	1
H-bond donors / acceptors	1 / 3
TPSA	52.3 Å²
Synonyms	(Z)-Ethyl 3-Aminocrotonate, (Z)-Ethyl 3-aminobut-2-enoate, ethyl (2E)-3-aminobut-2-enoate, Ethyl 3-amino-2-butenoate, ethyl 3-aminobut-2-enoate, Crotonic acid, 3-amino-, ethyl ester, Ethyl (2E)-3-amino-2-butenoate, 3-Amino-2-butenoic Acid Ethyl Ester, 2-Butenoic acid, 3-amino-, ethyl ester, (2E)-, .beta.-Aminocrotonic acid ethyl ester, Ethyl .beta.-aminocrotonate, 3-Aminocrotonic acid ethyl ester

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Signal word: Danger

Hazard statements

H314Causes severe skin burns and eye damage
H318Causes serious eye damage
H335May cause respiratory irritation

Precautionary statements: P260, P261, P264, P264 + P265, P271, P280, P301 + P330 + P331, P302 + P361 + P354, P304 + P340, P305 + P354 + P338, P316, P317, P319, P321, P363, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ethyl 3-aminocrotonate?

The CAS Registry Number of Ethyl 3-aminocrotonate is 626-34-6. It is also known as (Z)-Ethyl 3-Aminocrotonate, (Z)-Ethyl 3-aminobut-2-enoate, ethyl (2E)-3-aminobut-2-enoate.

What is the molecular formula and molecular weight of Ethyl 3-aminocrotonate?

Ethyl 3-aminocrotonate has the molecular formula C6H11NO2 and a molecular weight of 129.16 g/mol. Its IUPAC name is ethyl (E)-3-aminobut-2-enoate.

What is Ethyl 3-aminocrotonate used for?

Ethyl 3-aminocrotonate is supplied as a characterised reference material related to Allopurinol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ethyl 3-aminocrotonate can I order?

We supply Ethyl 3-aminocrotonate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ethyl 3-aminocrotonate?

Yes. Every lot of Ethyl 3-aminocrotonate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ethyl 3-aminocrotonate be shipped internationally?

Yes. Ethyl 3-aminocrotonate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.