Darunavir Ethanolate

Name: Darunavir Ethanolate
Brand: Vaqora Chemicals
SKU: VQ-025199

About Darunavir Ethanolate

Listed under CAS 635728-49-3, Darunavir Ethanolate is an impurity of Darunavir available from Vaqora Chemicals. Its molecular formula is C29H43N3O8S and its molecular weight is 593.7 g/mol. It is also known as Darunavir monoethanolate or Tmc114 ethanolate.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Darunavir to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Darunavir Ethanolate in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Darunavir

View every impurity, metabolite and intermediate we list for Darunavir.

Darunavir impurities

Specifications & identifiers

Chemical identifiers
Product name	Darunavir Ethanolate
Catalogue No.	VQ-025199
CAS Number	635728-49-3
IUPAC name	[(3aS,4R,6aR)-2,3,3a,4,5,6a-hexahydrofuro[2,3-b]furan-4-yl] N-[(2S,3R)-4-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-3-hydroxy-1-phenylbutan-2-yl]carbamate;ethanol
Molecular formula	C₂₉H₄₃N₃O₈S
Molecular weight	593.7 g/mol
Exact mass	593.2771
Grade	Reference Standard
HSN code	38229090
InChIKey	QWSHKNICRJHQCY-VBTXLZOXSA-N
SMILES	CCO.CC(C)CN(C[C@H]([C@H](CC1=CC=CC=C1)NC(=O)O[C@H]2CO[C@@H]3[C@H]2CCO3)O)S(=O)(=O)C4=CC=C(C=C4)N
PubChem CID	23725083

Physical properties
Physical form	Solid
H-bond donors / acceptors	4 / 10
TPSA	169 Å²
Synonyms	Darunavir monoethanolate, Tmc114 ethanolate, Darunavir (as ethanolate), Darunavir ethanolate (JAN), TMC114 (Ethanolate), darunavir ethanol solvate, Darunavir Ethanolate (Prezista), Darunavir ethanolate- Bio-X trade mark

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P319, P321, P330, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Darunavir Ethanolate?

The CAS Registry Number of Darunavir Ethanolate is 635728-49-3. It is also known as Darunavir monoethanolate, Tmc114 ethanolate, Darunavir (as ethanolate).

What is the molecular formula and molecular weight of Darunavir Ethanolate?

Darunavir Ethanolate has the molecular formula C29H43N3O8S and a molecular weight of 593.7 g/mol.

What is Darunavir Ethanolate used for?

Darunavir Ethanolate is supplied as a characterised reference material related to Darunavir. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Darunavir Ethanolate can I order?

We supply Darunavir Ethanolate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Darunavir Ethanolate?

Yes. Every lot of Darunavir Ethanolate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Darunavir Ethanolate be shipped internationally?

Yes. Darunavir Ethanolate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.