Methyl 3-(3,5-Di-tert-butyl-4-hydroxyphenyl)p… 6386-38-5

Name: Methyl 3-(3,5-Di-tert-butyl-4-hydroxyphenyl)propionate
Brand: Vaqora Chemicals
SKU: VQ-049830

About Methyl 3-(3,5-Di-tert-butyl-4-hydroxyphenyl)propionate

Methyl 3-(3,5-Di-tert-butyl-4-hydroxyphenyl)propionate (CAS 6386-38-5) is a metabolite or degradation product of Propofol offered by Vaqora Chemicals. The compound has the formula C18H28O3, corresponding to a molecular weight of 292.4 g/mol. Its systematic (IUPAC) name is methyl 3-(3,5-ditert-butyl-4-hydroxyphenyl)propanoate. Alternative names: methyl di-t-butyl hydroxyhydrocinnamate and RALOX 35.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Propofol, as well as in QC testing and ANDA/DMF documentation. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Methyl 3-(3,5-Di-tert-butyl-4-hydroxyphenyl)propionate in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Propofol

View every impurity, metabolite and intermediate we list for Propofol.

Propofol impurities

Specifications & identifiers

Chemical identifiers
Product name	Methyl 3-(3,5-Di-tert-butyl-4-hydroxyphenyl)propionate
Catalogue No.	VQ-049830
CAS Number	6386-38-5
IUPAC name	methyl 3-(3,5-ditert-butyl-4-hydroxyphenyl)propanoate
Molecular formula	C₁₈H₂₈O₃
Molecular weight	292.4 g/mol
Exact mass	292.2038
Grade	Reference Standard
HSN code	38229090
InChIKey	PXMJCECEFTYEKE-UHFFFAOYSA-N
SMILES	CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)CCC(=O)OC
PubChem CID	62603

Physical properties
Physical form	Solid
LogP (XLogP3)	5
H-bond donors / acceptors	1 / 3
TPSA	46.5 Å²
Synonyms	Methyl 3,5-di-tert-butyl-4-hydroxyhydrocinnamate, Benzenepropanoic acid, 3,5-bis(1,1-dimethylethyl)-4-hydroxy-, methyl ester, methyl di-t-butyl hydroxyhydrocinnamate, RALOX 35, Hydrocinnamic acid, 3,5-di-tert-butyl-4-hydroxy-, methyl ester, methyl (3,5-di-tert-butyl-4-hydroxyphenyl)propionate, 3-(3,5-di-tert-butyl-4-hydroxyphenyl)propionic acid methyl ester, methyl 3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoate, Methyl 3,5-bis(tert-butyl)-4-hydroxyhydrocinnamate, Methyl 3-[3,5-di(tert-butyl)-4-hydroxyphenyl]-propanoate

Safety & hazard information (GHS)

Harmful / irritant

Environmental hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H411Toxic to aquatic life with long lasting effects

Precautionary statements: P264, P270, P273, P301 + P317, P330, P391, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Methyl 3-(3,5-Di-tert-butyl-4-hydroxyphenyl)propionate?

The CAS Registry Number of Methyl 3-(3,5-Di-tert-butyl-4-hydroxyphenyl)propionate is 6386-38-5. It is also known as Methyl 3,5-di-tert-butyl-4-hydroxyhydrocinnamate, Benzenepropanoic acid, 3,5-bis(1,1-dimethylethyl)-4-hydroxy-, methyl ester, methyl di-t-butyl hydroxyhydrocinnamate.

What is the molecular formula and molecular weight of Methyl 3-(3,5-Di-tert-butyl-4-hydroxyphenyl)propionate?

Methyl 3-(3,5-Di-tert-butyl-4-hydroxyphenyl)propionate has the molecular formula C18H28O3 and a molecular weight of 292.4 g/mol. Its IUPAC name is methyl 3-(3,5-ditert-butyl-4-hydroxyphenyl)propanoate.

What is Methyl 3-(3,5-Di-tert-butyl-4-hydroxyphenyl)propionate used for?

Methyl 3-(3,5-Di-tert-butyl-4-hydroxyphenyl)propionate is supplied as a characterised reference material related to Propofol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Methyl 3-(3,5-Di-tert-butyl-4-hydroxyphenyl)propionate can I order?

We supply Methyl 3-(3,5-Di-tert-butyl-4-hydroxyphenyl)propionate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Methyl 3-(3,5-Di-tert-butyl-4-hydroxyphenyl)propionate?

Yes. Every lot of Methyl 3-(3,5-Di-tert-butyl-4-hydroxyphenyl)propionate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Methyl 3-(3,5-Di-tert-butyl-4-hydroxyphenyl)propionate be shipped internationally?

Yes. Methyl 3-(3,5-Di-tert-butyl-4-hydroxyphenyl)propionate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.