2,2,6,6-Tetramethyl-1-nitroso-4-piperidone

About 2,2,6,6-Tetramethyl-1-nitroso-4-piperidone

2,2,6,6-Tetramethyl-1-nitroso-4-piperidone is a nitrosamine impurity of Nitroso carrying the CAS registry number 640-01-7. With the molecular formula C9H16N2O2, it has a molar mass of 184.24 g/mol. Its systematic (IUPAC) name is 2,2,6,6-tetramethyl-1-nitrosopiperidin-4-one. It is also known as 2,2,6,6-Tetramethyl-1-nitroso-4-piperidinone or 4-Piperidinone,2,6,6-tetramethyl-1-nitroso-.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

Laboratories use this nitrosamine standard to develop and validate highly sensitive LC-MS/MS methods, to confirm limits of detection and to document nitrosamine risk assessments in regulatory submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 2,2,6,6-Tetramethyl-1-nitroso-4-piperidone is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Nitrosamine risk assessment
Trace LC-MS/MS quantitation
Method validation (AMV)
Regulatory submissions

Industries

Related to Nitroso

View every impurity, metabolite and intermediate we list for Nitroso.

Nitroso impurities

Specifications & identifiers

Chemical identifiers
Product name	2,2,6,6-Tetramethyl-1-nitroso-4-piperidone
Catalogue No.	VQ-040503
CAS Number	640-01-7
IUPAC name	2,2,6,6-tetramethyl-1-nitrosopiperidin-4-one
Molecular formula	C₉H₁₆N₂O₂
Molecular weight	184.24 g/mol
Exact mass	184.1212
Grade	Reference Standard
HSN code	38229090
InChIKey	PBOJDTWOZVDRPH-UHFFFAOYSA-N
SMILES	CC1(CC(=O)CC(N1N=O)(C)C)C
PubChem CID	69496

Physical properties
Physical form	Solid
LogP (XLogP3)	0.9
H-bond donors / acceptors	0 / 4
TPSA	49.7 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2,2,6,6-Tetramethyl-1-nitroso-4-piperidone?

The CAS Registry Number of 2,2,6,6-Tetramethyl-1-nitroso-4-piperidone is 640-01-7. It is also known as 4-Piperidinone, 2,2,6,6-tetramethyl-1-nitroso-, 2,2,6,6-Tetramethyl-1-nitroso-4-piperidinone, 4-Piperidinone,2,6,6-tetramethyl-1-nitroso-.

What is the molecular formula and molecular weight of 2,2,6,6-Tetramethyl-1-nitroso-4-piperidone?

2,2,6,6-Tetramethyl-1-nitroso-4-piperidone has the molecular formula C9H16N2O2 and a molecular weight of 184.24 g/mol. Its IUPAC name is 2,2,6,6-tetramethyl-1-nitrosopiperidin-4-one.

What is 2,2,6,6-Tetramethyl-1-nitroso-4-piperidone used for?

2,2,6,6-Tetramethyl-1-nitroso-4-piperidone is supplied as a characterised reference material related to Nitroso. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2,2,6,6-Tetramethyl-1-nitroso-4-piperidone can I order?

We supply 2,2,6,6-Tetramethyl-1-nitroso-4-piperidone in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2,2,6,6-Tetramethyl-1-nitroso-4-piperidone?

Yes. Every lot of 2,2,6,6-Tetramethyl-1-nitroso-4-piperidone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2,2,6,6-Tetramethyl-1-nitroso-4-piperidone be shipped internationally?

Yes. We export 2,2,6,6-Tetramethyl-1-nitroso-4-piperidone worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.