Nilotinib Impurity A
Synonyms: 3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline · 3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzenamine · 1-(3-Amino-5-trifluoromethylphenyl)-4-methylimidazole · 3-(4-Methylimidazol-1-yl)-5-trifluoromethylphenylamine
Nilotinib Impurity A (CAS 641571-11-1) – Nilotinib impurity standard. C11H10F3N3, MW 241.21. Buy from Vaqora Chemicals with COA and worldwide shipping.
About Nilotinib Impurity A
Nilotinib Impurity A is an impurity of Nilotinib carrying the CAS registry number 641571-11-1. The compound has the formula C11H10F3N3, corresponding to a molecular weight of 241.21 g/mol. The IUPAC name is 3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)aniline. Common synonyms include Nilotinib impurity A CRS and 3-(4-methylimidazol-1-yl)-5-trifluorometh.
The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Danger” with 7 hazard statements. Review the Safety Data Sheet before use.
As a characterised impurity of Nilotinib, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.
Vaqora Chemicals supplies Nilotinib Impurity A in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. Stock is available for quick dispatch.
Typical applications
- Analytical method development
- Method validation (AMV)
- QC release testing
- ANDA / DMF filings
Industries
View every impurity, metabolite and intermediate we list for Nilotinib.
Nilotinib impuritiesSpecifications & identifiers
| Product name | Nilotinib Impurity A |
|---|---|
| Catalogue No. | VQ-005362 |
| CAS Number | 641571-11-1 |
| IUPAC name | 3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)aniline |
| Molecular formula | C11H10F3N3 |
| Molecular weight | 241.21 g/mol |
| Exact mass | 241.0827 |
| Grade | Reference Standard |
| HSN code | 38229090 |
| InChIKey | WWTGXYAJVXKEKL-UHFFFAOYSA-N |
| SMILES | CC1=CN(C=N1)C2=CC(=CC(=C2)N)C(F)(F)F |
| PubChem CID | 12002825 |
| Physical form | Solid |
|---|---|
| LogP (XLogP3) | 2.3 |
| H-bond donors / acceptors | 1 / 5 |
| TPSA | 43.8 Ų |
| Synonyms | 3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline, 3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzenamine, 1-(3-Amino-5-trifluoromethylphenyl)-4-methylimidazole, 3-(4-Methylimidazol-1-yl)-5-trifluoromethylphenylamine, 5-(4-Methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)benzenamine, 5-(4-Methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)benzeneamine, Benzenamine, 3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)-, 3-(4-Methyl-1H-imidazol-1-yl)-5-trifluoromethylaniline, 3-(4-Methyl-1-imidazolyl)-5-(trifluoromethyl)aniline, Nilotinib impurity A CRS, 3-(4-methyl-1H-imidazole-1-yl)-5-(trifluoromethyl)aniline, 3-(4-methylimidazol-1-yl)-5-trifluorometh |
Safety & hazard information (GHS)
Signal word: Danger
Hazard statements
H301Toxic if swallowedH302Harmful if swallowedH315Causes skin irritationH318Causes serious eye damageH319Causes serious eye irritationH335May cause respiratory irritationH411Toxic to aquatic life with long lasting effects
Precautionary statements: P261, P264, P264 + P265, P270, P271, P273, P280, P301 + P316, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P305 + P354 + P338, P317, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P391, P403 + P233, P405, P501
Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.
Documents
Frequently asked questions
What is the CAS number of Nilotinib Impurity A?
The CAS Registry Number of Nilotinib Impurity A is 641571-11-1. It is also known as 3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline, 3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzenamine, 1-(3-Amino-5-trifluoromethylphenyl)-4-methylimidazole.
What is the molecular formula and molecular weight of Nilotinib Impurity A?
Nilotinib Impurity A has the molecular formula C11H10F3N3 and a molecular weight of 241.21 g/mol. Its IUPAC name is 3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)aniline.
What is Nilotinib Impurity A used for?
Nilotinib Impurity A is supplied as a characterised reference material related to Nilotinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.
Which grade and pack sizes of Nilotinib Impurity A can I order?
We supply Nilotinib Impurity A in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.
Do you provide a COA and SDS with Nilotinib Impurity A?
Yes. Every lot of Nilotinib Impurity A is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.
Can Nilotinib Impurity A be shipped internationally?
Yes. Nilotinib Impurity A is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.
Enquire about Nilotinib Impurity A
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