Desipramine-d3

About Desipramine-d3

Desipramine-d3 is a stable isotope labelled analogue related to Desipramine carrying the CAS registry number 65100-49-4. The compound has the formula C18H22N2, corresponding to a molecular weight of 269.4 g/mol. Systematically, it is named 3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N-(trideuteriomethyl)propan-1-amine. It is also known as TMID-0668.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

This isotope-labelled compound is used as an internal standard for LC-MS and LC-MS/MS quantitation of Desipramine and related analytes in bioanalytical, pharmacokinetic and impurity studies. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Desipramine

View every impurity, metabolite and intermediate we list for Desipramine.

Desipramine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Desipramine-d3
Catalogue No.	VQ-030129
CAS Number	65100-49-4
IUPAC name	3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N-(trideuteriomethyl)propan-1-amine
Molecular formula	C₁₈H₂₂N₂
Molecular weight	269.4 g/mol
Exact mass	269.1971
Grade	Reference Standard
HSN code	38229090
InChIKey	HCYAFALTSJYZDH-FIBGUPNXSA-N
SMILES	[2H]C([2H])([2H])NCCCN1C2=CC=CC=C2CCC3=CC=CC=C31
PubChem CID	45038865

Physical properties
Physical form	Solid
LogP (XLogP3)	4.9
H-bond donors / acceptors	1 / 2
TPSA	15.3 Å²

Safety & hazard information (GHS)

Harmful / irritant

Environmental hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects

Precautionary statements: P264, P270, P273, P301 + P317, P330, P391, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Desipramine-d3?

The CAS Registry Number of Desipramine-d3 is 65100-49-4. It is also known as 10,11-Dihydro-N-(methyl-d3)-5H-dibenz[b,f]azepine-5-propanamine, TMID-0668, 3-(10,11-Dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-(~2~H_3_)methylpropan-1-amine.

What is the molecular formula and molecular weight of Desipramine-d3?

Desipramine-d3 has the molecular formula C18H22N2 and a molecular weight of 269.4 g/mol. Its IUPAC name is 3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N-(trideuteriomethyl)propan-1-amine.

What is Desipramine-d3 used for?

Desipramine-d3 is supplied as a characterised reference material related to Desipramine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Desipramine-d3 can I order?

We supply Desipramine-d3 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Desipramine-d3?

Yes. Every lot of Desipramine-d3 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Desipramine-d3 be shipped internationally?

Yes. Desipramine-d3 is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.