Ivermectin EP Impurity B

About Ivermectin EP Impurity B

Ivermectin EP Impurity B is a pharmacopeial impurity of Ivermectin carrying the CAS registry number 65195-56-4. Formula C47H70O14, molecular weight 859.0 g/mol. Alternative names: Avermectin B1b and Abamectin B1b.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Danger” with 7 hazard statements. Review the Safety Data Sheet before use.

As a characterised impurity of Ivermectin, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Ivermectin EP Impurity B is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Ivermectin

View every impurity, metabolite and intermediate we list for Ivermectin.

Ivermectin impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Ivermectin EP Impurity B
Catalogue No.	VQ-026276
CAS Number	65195-56-4
IUPAC name	(1'R,2R,3S,4'S,6S,8'R,10'E,12'S,13'S,14'E,16'E,20'R,21'R,24'S)-21',24'-dihydroxy-12'-[(2R,4S,5S,6S)-5-[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-3,11',13',22'-tetramethyl-2-propan-2-ylspiro[2,3-dihydropyran-6,6'-3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene]-2'-one
Molecular formula	C₄₇H₇₀O₁₄
Molecular weight	859 g/mol
Exact mass	858.4766
Grade	Reference Standard
HSN code	38229090
InChIKey	ZFUKERYTFURFGA-PVVXTEPVSA-N
SMILES	C[C@H]1/C=C/C=C/2\CO[C@H]3[C@@]2([C@@H](C=C([C@H]3O)C)C(=O)O[C@H]4C[C@@H](C/C=C(/[C@H]1O[C@H]5C[C@@H]([C@H]([C@@H](O5)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O)OC)OC)\C)O[C@]7(C4)C=C[C@@H]([C@H](O7)C(C)C)C)O
PubChem CID	6858005

Physical properties
Physical form	Solid
LogP (XLogP3)	3.5
H-bond donors / acceptors	3 / 14
TPSA	170 Å²
Synonyms	Avermectin B1b, Abamectin B1b, Ivermectin - Impurity B, Abamectin komponente B1b, Antibiotic C 076B(sub 1b), Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-25-(1-methylethyl)-, AvermectinB1b, 5-O-Demethyl-25-de(1-methylpropyl)-25-(1-methylethyl)avermectin A1a, Avermectin A(sub 1a), 5-O-demethyl-25-de(1-methylpropyl)-25-(1-methylethyl)-

Safety & hazard information (GHS)

Toxic

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H300+H330Fatal if swallowed or if inhaled
H300Fatal if swallowed
H311Toxic in contact with skin
H330Fatal if inhaled
H372Causes damage to organs through prolonged or repeated exposure
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects

Precautionary statements: P203, P260, P262, P264, P270, P271, P273, P280, P284, P301 + P316, P302 + P352, P304 + P340, P316, P318, P319, P320, P321, P330, P361 + P364, P391, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ivermectin EP Impurity B?

The CAS Registry Number of Ivermectin EP Impurity B is 65195-56-4. It is also known as Avermectin B1b, Abamectin B1b, Ivermectin - Impurity B.

What is the molecular formula and molecular weight of Ivermectin EP Impurity B?

Ivermectin EP Impurity B has the molecular formula C47H70O14 and a molecular weight of 859 g/mol.

What is Ivermectin EP Impurity B used for?

Ivermectin EP Impurity B is supplied as a characterised reference material related to Ivermectin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ivermectin EP Impurity B can I order?

We supply Ivermectin EP Impurity B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ivermectin EP Impurity B?

Yes. Every lot of Ivermectin EP Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ivermectin EP Impurity B be shipped internationally?

Yes. Ivermectin EP Impurity B is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.