Sitagliptin phosphate (Monohydrate)

About Sitagliptin phosphate (Monohydrate)

Sitagliptin phosphate (Monohydrate) is a high-purity reference standard of Sitagliptin carrying the CAS registry number 654671-77-9. With the molecular formula C16H20F6N5O6P, it has a molar mass of 523.32 g/mol. It is also known as Sitagliptin Phosphate Hydrate or Sitagliptin Phosphate Monohydrate (WSM).

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Laboratories use this Sitagliptin standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Sitagliptin phosphate (Monohydrate) is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Sitagliptin

View every impurity, metabolite and intermediate we list for Sitagliptin.

Sitagliptin impurities

Specifications & identifiers

Chemical identifiers
Product name	Sitagliptin phosphate (Monohydrate)
Catalogue No.	VQ-028050
CAS Number	654671-77-9
IUPAC name	(3R)-3-amino-1-[3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one;phosphoric acid;hydrate
Molecular formula	C₁₆H₂₀F₆N₅O₆P
Molecular weight	523.32 g/mol
Exact mass	523.1055
Grade	Reference Standard
HSN code	38229090
InChIKey	GQPYTJVDPQTBQC-KLQYNRQASA-N
SMILES	C1CN2C(=NN=C2C(F)(F)F)CN1C(=O)C[C@@H](CC3=CC(=C(C=C3F)F)F)N.O.OP(=O)(O)O
PubChem CID	11591741

Physical properties
Physical form	Solid
H-bond donors / acceptors	5 / 15
TPSA	156 Å²
Synonyms	Sitagliptin Phosphate Hydrate, Sitagliptin Phosphate Monohydrate (WSM), sitagliptin monophosphate monohydrate, ONO-5435, Sitagliptin monophosphate, Sitagliptin monophosphate anhydrous, Phosphate, Sitagliptin, Anhydrous, Sitagliptin Phosphate, Phosphate Anhydrous, Sitagliptin, Monohydrate, Sitagliptin Phosphate, Phosphate Monohydrate, Sitagliptin

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Warning

Hazard statements

H319Causes serious eye irritation
H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements: P260, P264 + P265, P280, P305 + P351 + P338, P319, P337 + P317, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Sitagliptin phosphate (Monohydrate)?

The CAS Registry Number of Sitagliptin phosphate (Monohydrate) is 654671-77-9. It is also known as Sitagliptin Phosphate Hydrate, Sitagliptin Phosphate Monohydrate (WSM), sitagliptin monophosphate monohydrate.

What is the molecular formula and molecular weight of Sitagliptin phosphate (Monohydrate)?

Sitagliptin phosphate (Monohydrate) has the molecular formula C16H20F6N5O6P and a molecular weight of 523.32 g/mol.

What is Sitagliptin phosphate (Monohydrate) used for?

Sitagliptin phosphate (Monohydrate) is supplied as a characterised reference material related to Sitagliptin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Sitagliptin phosphate (Monohydrate) can I order?

We supply Sitagliptin phosphate (Monohydrate) in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Sitagliptin phosphate (Monohydrate)?

Yes. Every lot of Sitagliptin phosphate (Monohydrate) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Sitagliptin phosphate (Monohydrate) be shipped internationally?

Yes. Sitagliptin phosphate (Monohydrate) is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.