Asenapine

Name: Asenapine
Brand: Vaqora Chemicals
SKU: VQ-007325

About Asenapine

Asenapine (CAS 65576-45-6) is a high-purity reference standard of Asenapine offered by Vaqora Chemicals. Its molecular formula is C17H16ClNO and its molecular weight is 285.8 g/mol. Systematically, it is named (2S,6S)-9-chloro-4-methyl-13-oxa-4-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7(12),8,10,14,16-hexaene. Alternative names: (±)-Asenapine and Saphris.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As a reference sample of Asenapine, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Asenapine in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Asenapine

View every impurity, metabolite and intermediate we list for Asenapine.

Asenapine impurities

Specifications & identifiers

Chemical identifiers
Product name	Asenapine
Catalogue No.	VQ-007325
CAS Number	65576-45-6
Other CAS	85650-56-2
IUPAC name	(2S,6S)-9-chloro-4-methyl-13-oxa-4-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7(12),8,10,14,16-hexaene
Molecular formula	C₁₇H₁₆ClNO
Molecular weight	285.8 g/mol
Exact mass	285.092
Grade	Reference Standard
HSN code	38229090
InChIKey	VSWBSWWIRNCQIJ-HUUCEWRRSA-N
SMILES	CN1C[C@H]2[C@H](C1)C3=C(C=CC(=C3)Cl)OC4=CC=CC=C24
PubChem CID	163091

Physical properties
Physical form	Solid
LogP (XLogP3)	3.8
H-bond donors / acceptors	0 / 2
TPSA	12.5 Å²
Synonyms	(±)-Asenapine, Trans-5-Chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz[2,3:6,7] oxepino[4,5-c]pyrrole, Saphris, Sycrest, Alkepin, trans-5-Chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz(2,3:6,7)oxepino(4,5-c)pyrrole, 1H-Dibenz(2,3:6,7)oxepino(4,5-c)pyrrole, 5-chloro-2,3,3a,12b-tetrahydro-2-methyl-, trans-, (S,S)-asenapine, (+/-)-Asenapine, Asenapine (INN), (3aS,12bS)-5-Chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrole, Secuado (TN)

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Asenapine?

The CAS Registry Number of Asenapine is 65576-45-6. It is also known as (±)-Asenapine, Trans-5-Chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz[2,3:6,7] oxepino[4,5-c]pyrrole, Saphris.

What is the molecular formula and molecular weight of Asenapine?

Asenapine has the molecular formula C17H16ClNO and a molecular weight of 285.8 g/mol. Its IUPAC name is (2S,6S)-9-chloro-4-methyl-13-oxa-4-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7(12),8,10,14,16-hexaene.

What is Asenapine used for?

Asenapine is supplied as a characterised reference material related to Asenapine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Asenapine can I order?

We supply Asenapine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Asenapine?

Yes. Every lot of Asenapine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Asenapine be shipped internationally?

Yes. Asenapine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.