N-Nitroso-Diclofenac

Name: N-Nitroso-Diclofenac
Brand: Vaqora Chemicals
SKU: VQ-021206

About N-Nitroso-Diclofenac

Listed under CAS 66505-80-4, N-Nitroso-Diclofenac is a nitrosamine impurity of Diclofenac available from Vaqora Chemicals. With the molecular formula C14H10Cl2N2O3, it has a molar mass of 325.1 g/mol. Its systematic (IUPAC) name is 2-[2-(2,6-dichloro-N-nitrosoanilino)phenyl]acetic acid. Alternative names: NCX-284 and N-Nitroso-Diclofec.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

It is used as a reference standard for trace-level detection and quantitation of nitrosamine impurities by LC-MS/MS or GC-MS, supporting nitrosamine risk assessments for Diclofenac, method validation (AMV) and regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer N-Nitroso-Diclofenac in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Nitrosamine risk assessment
Trace LC-MS/MS quantitation
Method validation (AMV)
Regulatory submissions

Industries

Related to Diclofenac

View every impurity, metabolite and intermediate we list for Diclofenac.

Diclofenac impurities

Specifications & identifiers

Chemical identifiers
Product name	N-Nitroso-Diclofenac
Catalogue No.	VQ-021206
CAS Number	66505-80-4
IUPAC name	2-[2-(2,6-dichloro-N-nitrosoanilino)phenyl]acetic acid
Molecular formula	C₁₄H₁₀Cl₂N₂O₃
Molecular weight	325.1 g/mol
Exact mass	324.0068
Grade	Reference Standard
HSN code	38229090
InChIKey	MRJVSFHDJGEONX-UHFFFAOYSA-N
SMILES	C1=CC=C(C(=C1)CC(=O)O)N(C2=C(C=CC=C2Cl)Cl)N=O
PubChem CID	9797358

Physical properties
Physical form	Solid
LogP (XLogP3)	4
H-bond donors / acceptors	1 / 5
TPSA	70 Å²
Synonyms	NCX-284, 2-(2-((2,6-Dichlorophenyl)(nitroso)amino)phenyl)acetic acid, Benzeneacetic acid, 2-[(2,6-dichlorophenyl)nitrosoamino]-, N-Nitroso-Diclofec, 2-[(2,6-Dichlorophenyl)nitrosoamino]benzeneacetic acid, {2-[(2,6-Dichlorophenyl)(nitroso)amino]phenyl}acetic acid, 2-[2-(2,6-dichloro-N-nitroso-anilino)phenyl]acetic acid, L-(+)-Tartaric Acid Potassium Sodium Salt Tetrahydrate (Rochelle's Salt)

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Nitroso-Diclofenac?

The CAS Registry Number of N-Nitroso-Diclofenac is 66505-80-4. It is also known as NCX-284, 2-(2-((2,6-Dichlorophenyl)(nitroso)amino)phenyl)acetic acid, Benzeneacetic acid, 2-[(2,6-dichlorophenyl)nitrosoamino]-.

What is the molecular formula and molecular weight of N-Nitroso-Diclofenac?

N-Nitroso-Diclofenac has the molecular formula C14H10Cl2N2O3 and a molecular weight of 325.1 g/mol. Its IUPAC name is 2-[2-(2,6-dichloro-N-nitrosoanilino)phenyl]acetic acid.

What is N-Nitroso-Diclofenac used for?

N-Nitroso-Diclofenac is supplied as a characterised reference material related to Diclofenac. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Nitroso-Diclofenac can I order?

We supply N-Nitroso-Diclofenac in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Nitroso-Diclofenac?

Yes. Every lot of N-Nitroso-Diclofenac is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Nitroso-Diclofenac be shipped internationally?

Yes. We export N-Nitroso-Diclofenac worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.