Nilotinib 3-Pyridinyl Impurity

Name: Nilotinib 3-Pyridinyl Impurity
Brand: Vaqora Chemicals
SKU: VQ-032158

About Nilotinib 3-Pyridinyl Impurity

Listed under CAS 66521-66-2, Nilotinib 3-Pyridinyl Impurity is an impurity of Nilotinib available from Vaqora Chemicals. Its molecular formula is C9H8N4 and its molecular weight is 172.19 g/mol. Systematically, it is named 4-pyridin-3-ylpyrimidin-2-amine. Common synonyms include 4-(pyridin-3-yl)pyrimidin-2-amine and 4-(3-Pyridinyl)-2-aminopyrimidine.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

As a characterised impurity of Nilotinib, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Nilotinib 3-Pyridinyl Impurity is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Nilotinib

View every impurity, metabolite and intermediate we list for Nilotinib.

Nilotinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Nilotinib 3-Pyridinyl Impurity
Catalogue No.	VQ-032158
CAS Number	66521-66-2
IUPAC name	4-pyridin-3-ylpyrimidin-2-amine
Molecular formula	C₉H₈N₄
Molecular weight	172.19 g/mol
Exact mass	172.0749
Grade	Reference Standard
HSN code	38229090
InChIKey	LQHQKYWYKPLKCH-UHFFFAOYSA-N
SMILES	C1=CC(=CN=C1)C2=NC(=NC=C2)N
PubChem CID	12450582

Physical properties
Physical form	Solid
LogP (XLogP3)	0.4
H-bond donors / acceptors	1 / 4
TPSA	64.7 Å²
Synonyms	4-(pyridin-3-yl)pyrimidin-2-amine, 4-(3-Pyridinyl)-2-aminopyrimidine, 4-(3-Pyridinyl)-2-pyrimidine amine, 4-(3-Pyridinyl)-2-pyrimidinamine, 2-Amino-4-(3-pyridinyl)-pyrimidine, 2-amino-4-pyridyl-pyrimidine, 4-(pyridin-3-yl)pyrimidin-2-ylamine, 2xdk, 4-(3-pyridyl)pyrimidin-2-amine, 4-(3-pyridyl)-2-pyrimidine-amine, 4-(3-pyridyl)pyrimidine-2-ylamine, 4-(pyridin-3-yl)-pyrimidin-2-ylamine

Safety & hazard information (GHS)

Toxic

Harmful / irritant

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P316, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Nilotinib 3-Pyridinyl Impurity?

The CAS Registry Number of Nilotinib 3-Pyridinyl Impurity is 66521-66-2. It is also known as 4-(pyridin-3-yl)pyrimidin-2-amine, 4-(3-Pyridinyl)-2-aminopyrimidine, 4-(3-Pyridinyl)-2-pyrimidine amine.

What is the molecular formula and molecular weight of Nilotinib 3-Pyridinyl Impurity?

Nilotinib 3-Pyridinyl Impurity has the molecular formula C9H8N4 and a molecular weight of 172.19 g/mol. Its IUPAC name is 4-pyridin-3-ylpyrimidin-2-amine.

What is Nilotinib 3-Pyridinyl Impurity used for?

Nilotinib 3-Pyridinyl Impurity is supplied as a characterised reference material related to Nilotinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Nilotinib 3-Pyridinyl Impurity can I order?

We supply Nilotinib 3-Pyridinyl Impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Nilotinib 3-Pyridinyl Impurity?

Yes. Every lot of Nilotinib 3-Pyridinyl Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Nilotinib 3-Pyridinyl Impurity be shipped internationally?

Yes. Nilotinib 3-Pyridinyl Impurity is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.