3-Bromo-5-nitrobenzotrifluoride

Name: 3-Bromo-5-nitrobenzotrifluoride
Brand: Vaqora Chemicals
SKU: VQ-027253

About 3-Bromo-5-nitrobenzotrifluoride

Vaqora Chemicals supplies 3-Bromo-5-nitrobenzotrifluoride, an impurity of Nilotinib registered under CAS number 630125-49-4. Its molecular formula is C7H3BrF3NO2 and its molecular weight is 270.0 g/mol. Systematically, it is named 1-bromo-3-nitro-5-(trifluoromethyl)benzene. Alternative names: 1-Bromo-3-nitro-5-trifluoromethylbenzene and 1-Bromo-3-nitro-5-trifluoromethyl-benzene.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

This Nilotinib impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 3-Bromo-5-nitrobenzotrifluoride is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Nilotinib

View every impurity, metabolite and intermediate we list for Nilotinib.

Nilotinib impurities

Specifications & identifiers

Chemical identifiers
Product name	3-Bromo-5-nitrobenzotrifluoride
Catalogue No.	VQ-027253
CAS Number	630125-49-4
IUPAC name	1-bromo-3-nitro-5-(trifluoromethyl)benzene
Molecular formula	C₇H₃BrF₃NO₂
Molecular weight	270 g/mol
Exact mass	268.9299
Grade	Reference Standard
HSN code	38229090
InChIKey	YHTVYRKVFAFVLP-UHFFFAOYSA-N
SMILES	C1=C(C=C(C=C1[N+](=O)[O-])Br)C(F)(F)F
PubChem CID	7015411

Physical properties
Physical form	Solid
LogP (XLogP3)	3.3
H-bond donors / acceptors	0 / 5
TPSA	45.8 Å²
Synonyms	1-Bromo-3-nitro-5-trifluoromethylbenzene, 1-Bromo-3-nitro-5-trifluoromethyl-benzene, 3-bromo-5-trifluoromethylnitrobenzene, Benzene, 1-bromo-3-nitro-5-(trifluoromethyl)-, 3-bromo-1-nitro-5-(trifluoromethyl)benzene

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302+H312+H332Harmful if swallowed, in contact with skin or if inhaled
H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 3-Bromo-5-nitrobenzotrifluoride?

The CAS Registry Number of 3-Bromo-5-nitrobenzotrifluoride is 630125-49-4. It is also known as 1-Bromo-3-nitro-5-trifluoromethylbenzene, 1-Bromo-3-nitro-5-trifluoromethyl-benzene, 3-bromo-5-trifluoromethylnitrobenzene.

What is the molecular formula and molecular weight of 3-Bromo-5-nitrobenzotrifluoride?

3-Bromo-5-nitrobenzotrifluoride has the molecular formula C7H3BrF3NO2 and a molecular weight of 270 g/mol. Its IUPAC name is 1-bromo-3-nitro-5-(trifluoromethyl)benzene.

What is 3-Bromo-5-nitrobenzotrifluoride used for?

3-Bromo-5-nitrobenzotrifluoride is supplied as a characterised reference material related to Nilotinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 3-Bromo-5-nitrobenzotrifluoride can I order?

We supply 3-Bromo-5-nitrobenzotrifluoride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 3-Bromo-5-nitrobenzotrifluoride?

Yes. Every lot of 3-Bromo-5-nitrobenzotrifluoride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 3-Bromo-5-nitrobenzotrifluoride be shipped internationally?

Yes. 3-Bromo-5-nitrobenzotrifluoride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.