Bisoprolol

About Bisoprolol

Bisoprolol is a high-purity reference standard of Bisoprolol carrying the CAS registry number 66722-44-9. Its molecular formula is C18H31NO4 and its molecular weight is 325.4 g/mol. Systematically, it is named 1-(propan-2-ylamino)-3-[4-(2-propan-2-yloxyethoxymethyl)phenoxy]propan-2-ol. It is also known as Cardensiel or Konkor.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Warning” with 1 hazard statement. Review the Safety Data Sheet before use.

Laboratories use this Bisoprolol standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer Bisoprolol in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Bisoprolol

View every impurity, metabolite and intermediate we list for Bisoprolol.

Bisoprolol impurities

Specifications & identifiers

Chemical identifiers
Product name	Bisoprolol
Catalogue No.	VQ-007350
CAS Number	66722-44-9
IUPAC name	1-(propan-2-ylamino)-3-[4-(2-propan-2-yloxyethoxymethyl)phenoxy]propan-2-ol
Molecular formula	C₁₈H₃₁NO₄
Molecular weight	325.4 g/mol
Exact mass	325.2253
Grade	Reference Standard
HSN code	38229090
InChIKey	VHYCDWMUTMEGQY-UHFFFAOYSA-N
SMILES	CC(C)NCC(COC1=CC=C(C=C1)COCCOC(C)C)O
PubChem CID	2405

Physical properties
Physical form	Solid
LogP (XLogP3)	1.9
H-bond donors / acceptors	2 / 5
TPSA	60 Å²
Synonyms	1-[4-[[2-(1- Methylethoxy)ethoxy]methyl]phenoxy]-3-[(1-methylethyl)amino]-2-propanol, (2RS)-1-[4-[[2-(1-Methylethoxy)ethoxy]methyl]phenoxy]-3-[(1-methylethyl)amino]propan-2-ol, 1-[4-(2-Isopropoxy-ethoxymethyl)-phenoxy]-3-isopropylamino-propan-2-ol, 1-(P ropan-2-ylamino)-3-[4-(2-propan-2-yloxyethoxymethyl)phenoxy]propan-2-ol, Cardensiel, Konkor, EMD 33 512, (RS)-1-(4-(2-Isopropoxyethoxymethyl)phenoxy)-3-(isopropylamino)-2-propanol, (+-)-1-((alpha-(2-Isopropoxyethoxy)-p-tolyl)oxy)-3-(isopropylamino)-2-propanol, Bisoprololum (Latin), [2-hydroxy-3-(4-{[2-(propan-2-yloxy)ethoxy]methyl}phenoxy)propyl](propan-2-yl)amine, (2-hydroxy-3-(4-((2-(propan-2-yloxy)ethoxy)methyl)phenoxy)propyl)(propan-2-yl)amine

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Bisoprolol?

The CAS Registry Number of Bisoprolol is 66722-44-9. It is also known as 1-[4-[[2-(1- Methylethoxy)ethoxy]methyl]phenoxy]-3-[(1-methylethyl)amino]-2-propanol, (2RS)-1-[4-[[2-(1-Methylethoxy)ethoxy]methyl]phenoxy]-3-[(1-methylethyl)amino]propan-2-ol, 1-[4-(2-Isopropoxy-ethoxymethyl)-phenoxy]-3-isopropylamino-propan-2-ol.

What is the molecular formula and molecular weight of Bisoprolol?

Bisoprolol has the molecular formula C18H31NO4 and a molecular weight of 325.4 g/mol. Its IUPAC name is 1-(propan-2-ylamino)-3-[4-(2-propan-2-yloxyethoxymethyl)phenoxy]propan-2-ol.

What is Bisoprolol used for?

Bisoprolol is supplied as a characterised reference material related to Bisoprolol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Bisoprolol can I order?

We supply Bisoprolol in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Bisoprolol?

Yes. Every lot of Bisoprolol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Bisoprolol be shipped internationally?

Yes. Bisoprolol is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.