5-Methyl-4-isoxazolecarbonyl chloride

Name: 5-Methyl-4-isoxazolecarbonyl chloride
Brand: Vaqora Chemicals
SKU: VQ-034137

About 5-Methyl-4-isoxazolecarbonyl chloride

Vaqora Chemicals supplies 5-Methyl-4-isoxazolecarbonyl chloride, an impurity of Teriflunomide registered under CAS number 67305-24-2. With the molecular formula C5H4ClNO2, it has a molar mass of 145.54 g/mol. The IUPAC name is 5-methyl-1,2-oxazole-4-carbonyl chloride. Alternative names: 5-Methylisoxazole-4-carbonyl chloride and 5-Methyl-isoxazole-4-carbonyl chloride.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Teriflunomide to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 5-Methyl-4-isoxazolecarbonyl chloride is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Teriflunomide

View every impurity, metabolite and intermediate we list for Teriflunomide.

Teriflunomide impurities

Specifications & identifiers

Chemical identifiers
Product name	5-Methyl-4-isoxazolecarbonyl chloride
Catalogue No.	VQ-034137
CAS Number	67305-24-2
IUPAC name	5-methyl-1,2-oxazole-4-carbonyl chloride
Molecular formula	C₅H₄ClNO₂
Molecular weight	145.54 g/mol
Exact mass	144.9931
Grade	Reference Standard
HSN code	38229090
InChIKey	ZKAQPVQEYCFRTK-UHFFFAOYSA-N
SMILES	CC1=C(C=NO1)C(=O)Cl
PubChem CID	2759917

Physical properties
Physical form	Solid
LogP (XLogP3)	1.3
H-bond donors / acceptors	0 / 3
TPSA	43.1 Å²
Synonyms	5-Methylisoxazole-4-carbonyl chloride, 5-Methyl-isoxazole-4-carbonyl chloride, 4-isoxazolecarbonyl chloride, 5-methyl-, 4-Isoxazolecarbonylchloride, 5-methyl-, Methyl-4-isoxazolecarbonyl chloride, 5-methylisoxazole-4-carbonylchloride, 4-isoxazolecarbonyl chloride, 5-methyl, 5-Methylisoxazol-4-yl carbonyl chloride, 5-methyl-4-isoxazolecarboxylic acid chloride, 5-methylisoxazole-4-carboxylic acid chloride

Safety & hazard information (GHS)

Corrosive

Signal word: Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements: P260, P264, P280, P301 + P330 + P331, P302 + P361 + P354, P304 + P340, P305 + P354 + P338, P316, P321, P363, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 5-Methyl-4-isoxazolecarbonyl chloride?

The CAS Registry Number of 5-Methyl-4-isoxazolecarbonyl chloride is 67305-24-2. It is also known as 5-Methylisoxazole-4-carbonyl chloride, 5-Methyl-isoxazole-4-carbonyl chloride, 4-isoxazolecarbonyl chloride, 5-methyl-.

What is the molecular formula and molecular weight of 5-Methyl-4-isoxazolecarbonyl chloride?

5-Methyl-4-isoxazolecarbonyl chloride has the molecular formula C5H4ClNO2 and a molecular weight of 145.54 g/mol. Its IUPAC name is 5-methyl-1,2-oxazole-4-carbonyl chloride.

What is 5-Methyl-4-isoxazolecarbonyl chloride used for?

5-Methyl-4-isoxazolecarbonyl chloride is supplied as a characterised reference material related to Teriflunomide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 5-Methyl-4-isoxazolecarbonyl chloride can I order?

We supply 5-Methyl-4-isoxazolecarbonyl chloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 5-Methyl-4-isoxazolecarbonyl chloride?

Yes. Every lot of 5-Methyl-4-isoxazolecarbonyl chloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 5-Methyl-4-isoxazolecarbonyl chloride be shipped internationally?

Yes. 5-Methyl-4-isoxazolecarbonyl chloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.