N-Nitrosoguanidine

Name: N-Nitrosoguanidine
Brand: Vaqora Chemicals
SKU: VQ-039972

About N-Nitrosoguanidine

N-Nitrosoguanidine (CAS 674-81-7) is a nitrosamine impurity of Nitroso Impurity offered by Vaqora Chemicals. With the molecular formula CH4N4O, it has a molar mass of 88.07 g/mol. The IUPAC name is 2-nitrosoguanidine. It is also known as Nitrosoguanidine or Nitrosoguanidin.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

It is used as a reference standard for trace-level detection and quantitation of nitrosamine impurities by LC-MS/MS or GC-MS, supporting nitrosamine risk assessments for Nitroso Impurity, method validation (AMV) and regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer N-Nitrosoguanidine in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Nitrosamine risk assessment
Trace LC-MS/MS quantitation
Method validation (AMV)
Regulatory submissions

Industries

Related to Nitroso Impurity

View every impurity, metabolite and intermediate we list for Nitroso Impurity.

Nitroso Impurity impurities

Specifications & identifiers

Chemical identifiers
Product name	N-Nitrosoguanidine
Catalogue No.	VQ-039972
CAS Number	674-81-7
IUPAC name	2-nitrosoguanidine
Molecular formula	CH₄N₄O
Molecular weight	88.07 g/mol
Exact mass	88.0385
Grade	Reference Standard
HSN code	38229090
InChIKey	WTLKTXIHIHFSGU-UHFFFAOYSA-N
SMILES	C(=NN=O)(N)N
PubChem CID	12660

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.9
H-bond donors / acceptors	2 / 3
TPSA	93.8 Å²
Synonyms	Nitrosoguanidine, Nitrosoguanidin, Guanidine, N-nitroso-, Initiating explosive nitrosoguanidine (DOT), Guanidine, nitroso, 1-nitrosoguanidine, isonitroso-guanidine, Initiating explosive nitrosoguanidine, N''-Oxocarbonohydrazonic diamide

Safety & hazard information (GHS)

Flammable

Signal word: Danger

Hazard statements

H242Heating may cause a fire

Precautionary statements: P210, P234, P235, P240, P280, P370 + P378, P403, P410, P411, P420, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Nitrosoguanidine?

The CAS Registry Number of N-Nitrosoguanidine is 674-81-7. It is also known as Nitrosoguanidine, Nitrosoguanidin, Guanidine, N-nitroso-.

What is the molecular formula and molecular weight of N-Nitrosoguanidine?

N-Nitrosoguanidine has the molecular formula CH4N4O and a molecular weight of 88.07 g/mol. Its IUPAC name is 2-nitrosoguanidine.

What is N-Nitrosoguanidine used for?

N-Nitrosoguanidine is supplied as a characterised reference material related to Nitroso Impurity. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Nitrosoguanidine can I order?

We supply N-Nitrosoguanidine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Nitrosoguanidine?

Yes. Every lot of N-Nitrosoguanidine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Nitrosoguanidine be shipped internationally?

Yes. N-Nitrosoguanidine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.