Fluocinolone acetonide EP Impurity E

About Fluocinolone acetonide EP Impurity E

Fluocinolone acetonide EP Impurity E is a pharmacopeial impurity of Fluocinolone acetonide carrying the CAS registry number 68352-03-4. Formula C24H29FO6, molecular weight 432.5 g/mol. Alternative names: Fluocinolone Acetonide - Impurity E and 9beta,11beta-Fluocinolone acetonide.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

As a characterised impurity of Fluocinolone acetonide, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer Fluocinolone acetonide EP Impurity E in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Fluocinolone acetonide

View every impurity, metabolite and intermediate we list for Fluocinolone acetonide.

Fluocinolone acetonide impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Fluocinolone acetonide EP Impurity E
Catalogue No.	VQ-022674
CAS Number	68352-03-4
IUPAC name	(1S,3S,5S,6S,10R,12S,13S,15S,21S)-15-fluoro-6-(2-hydroxyacetyl)-5,8,8,21-tetramethyl-2,7,9-trioxahexacyclo[11.8.0.01,3.05,12.06,10.016,21]henicosa-16,19-dien-18-one
Molecular formula	C₂₄H₂₉FO₆
Molecular weight	432.5 g/mol
Exact mass	432.1948
Grade	Reference Standard
HSN code	38229090
InChIKey	BYWOITQBHUGMQO-CHWIRLIISA-N
SMILES	C[C@]12C[C@H]3[C@]4(O3)[C@H]([C@@H]1C[C@@H]5[C@]2(OC(O5)(C)C)C(=O)CO)C[C@@H](C6=CC(=O)C=C[C@]46C)F
PubChem CID	76962589

Physical properties
Physical form	Solid
LogP (XLogP3)	2.4
H-bond donors / acceptors	1 / 7
TPSA	85.4 Å²

Safety & hazard information (GHS)

Toxic

Health hazard

Signal word: Danger

Hazard statements

H300Fatal if swallowed
H312+H332Harmful in contact with skin or if inhaled
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
H360May damage fertility or the unborn child

Precautionary statements: P203, P261, P264, P264 + P265, P270, P271, P280, P301 + P316, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P318, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Fluocinolone acetonide EP Impurity E?

The CAS Registry Number of Fluocinolone acetonide EP Impurity E is 68352-03-4. It is also known as Fluocinolone Acetonide - Impurity E, 9beta,11beta-Fluocinolone acetonide.

What is the molecular formula and molecular weight of Fluocinolone acetonide EP Impurity E?

Fluocinolone acetonide EP Impurity E has the molecular formula C24H29FO6 and a molecular weight of 432.5 g/mol.

What is Fluocinolone acetonide EP Impurity E used for?

Fluocinolone acetonide EP Impurity E is supplied as a characterised reference material related to Fluocinolone acetonide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Fluocinolone acetonide EP Impurity E can I order?

We supply Fluocinolone acetonide EP Impurity E in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Fluocinolone acetonide EP Impurity E?

Yes. Every lot of Fluocinolone acetonide EP Impurity E is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Fluocinolone acetonide EP Impurity E be shipped internationally?

Yes. Fluocinolone acetonide EP Impurity E is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.