Atorvastatin EP Impurity C (Freebase)

Name: Atorvastatin EP Impurity C (Freebase)
Brand: Vaqora Chemicals
SKU: VQ-006252

About Atorvastatin EP Impurity C (Freebase)

Listed under CAS 693794-20-6, Atorvastatin EP Impurity C (Freebase) is a pharmacopeial impurity of Atorvastatin available from Vaqora Chemicals. Formula C33H34F2N2O5, molecular weight 576.6 g/mol. The IUPAC name is (3R,5R)-7-[2,3-bis(4-fluorophenyl)-4-(phenylcarbamoyl)-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoic acid. It is also known as Fluoroatorvastatin or Difluoro Atorvastatin.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

As a characterised impurity of Atorvastatin, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Atorvastatin

View every impurity, metabolite and intermediate we list for Atorvastatin.

Atorvastatin impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Atorvastatin EP Impurity C (Freebase)
Catalogue No.	VQ-006252
CAS Number	693794-20-6
IUPAC name	(3R,5R)-7-[2,3-bis(4-fluorophenyl)-4-(phenylcarbamoyl)-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoic acid
Molecular formula	C₃₃H₃₄F₂N₂O₅
Molecular weight	576.6 g/mol
Exact mass	576.2436
Grade	Reference Standard
HSN code	38229090
InChIKey	UNKLVVGSJZVOBR-KAYWLYCHSA-N
SMILES	CC(C)C1=C(C(=C(N1CC[C@H](C[C@H](CC(=O)O)O)O)C2=CC=C(C=C2)F)C3=CC=C(C=C3)F)C(=O)NC4=CC=CC=C4
PubChem CID	10076865

Physical properties
Physical form	Solid
LogP (XLogP3)	5.1
H-bond donors / acceptors	4 / 7
TPSA	112 Å²
Synonyms	Fluoroatorvastatin, Difluoro Atorvastatin, Atorvastatin calcium trihydrate impurity C, Atorvastatin IMpurity C, Atorvastatin calcium trihydrate impurity C, Fluoroatorvastatin

Safety & hazard information (GHS)

Health hazard

Signal word: Danger

Hazard statements

H319Causes serious eye irritation
H360May damage fertility or the unborn child

Precautionary statements: P203, P264 + P265, P280, P305 + P351 + P338, P318, P337 + P317, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Atorvastatin EP Impurity C (Freebase)?

The CAS Registry Number of Atorvastatin EP Impurity C (Freebase) is 693794-20-6. It is also known as Fluoroatorvastatin, Difluoro Atorvastatin, Atorvastatin calcium trihydrate impurity C.

What is the molecular formula and molecular weight of Atorvastatin EP Impurity C (Freebase)?

Atorvastatin EP Impurity C (Freebase) has the molecular formula C33H34F2N2O5 and a molecular weight of 576.6 g/mol. Its IUPAC name is (3R,5R)-7-[2,3-bis(4-fluorophenyl)-4-(phenylcarbamoyl)-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoic acid.

What is Atorvastatin EP Impurity C (Freebase) used for?

Atorvastatin EP Impurity C (Freebase) is supplied as a characterised reference material related to Atorvastatin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Atorvastatin EP Impurity C (Freebase) can I order?

We supply Atorvastatin EP Impurity C (Freebase) in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Atorvastatin EP Impurity C (Freebase)?

Yes. Every lot of Atorvastatin EP Impurity C (Freebase) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Atorvastatin EP Impurity C (Freebase) be shipped internationally?

Yes. Atorvastatin EP Impurity C (Freebase) is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.