8,8'-((1R,2R,3S,4S)-2,4-Bis(3,4-dimethoxyphen… 702697-27-6

Name: 8,8'-((1R,2R,3S,4S)-2,4-Bis(3,4-dimethoxyphenyl)cyclobutane-1,3-diyl)bis(1,3-diethyl-7-methyl-3,7-dihydro-1H-purine-2,6-dione)
Brand: Vaqora Chemicals
SKU: VQ-035452

About 8,8'-((1R,2R,3S,4S)-2,4-Bis(3,4-dimethoxyphenyl)cyclobutane-1,3-diyl)bis(1,3-diethyl-7-methyl-3,7-dihydro-1H-purine-2,6-dione)

8,8'-((1R,2R,3S,4S)-2,4-Bis(3,4-dimethoxyphenyl)cyclobutane-1,3-diyl)bis(1,3-diethyl-7-methyl-3,7-dihydro-1H-purine-2,6-dione) (CAS 702697-27-6) is an impurity of Istradefylline offered by Vaqora Chemicals. With the molecular formula C40H48N8O8, it has a molar mass of 768.9 g/mol.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Istradefylline to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 8,8'-((1R,2R,3S,4S)-2,4-Bis(3,4-dimethoxyphenyl)cyclobutane-1,3-diyl)bis(1,3-diethyl-7-methyl-3,7-dihydro-1H-purine-2,6-dione) in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Istradefylline

View every impurity, metabolite and intermediate we list for Istradefylline.

Istradefylline impurities

Specifications & identifiers

Chemical identifiers
Product name	8,8'-((1R,2R,3S,4S)-2,4-Bis(3,4-dimethoxyphenyl)cyclobutane-1,3-diyl)bis(1,3-diethyl-7-methyl-3,7-dihydro-1H-purine-2,6-dione)
Catalogue No.	VQ-035452
CAS Number	702697-27-6
IUPAC name	8-[3-(1,3-diethyl-7-methyl-2,6-dioxopurin-8-yl)-2,4-bis(3,4-dimethoxyphenyl)cyclobutyl]-1,3-diethyl-7-methylpurine-2,6-dione
Molecular formula	C₄₀H₄₈N₈O₈
Molecular weight	768.9 g/mol
Exact mass	768.3595
Grade	Reference Standard
HSN code	38229090
InChIKey	PRWCVMGTVZGZJW-UHFFFAOYSA-N
SMILES	CCN1C2=C(C(=O)N(C1=O)CC)N(C(=N2)C3C(C(C3C4=CC(=C(C=C4)OC)OC)C5=NC6=C(N5C)C(=O)N(C(=O)N6CC)CC)C7=CC(=C(C=C7)OC)OC)C
PubChem CID	11320240

Physical properties
Physical form	Solid
LogP (XLogP3)	3.7
H-bond donors / acceptors	0 / 10
TPSA	154 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 8,8'-((1R,2R,3S,4S)-2,4-Bis(3,4-dimethoxyphenyl)cyclobutane-1,3-diyl)bis(1,3-diethyl-7-methyl-3,7-dihydro-1H-purine-2,6-dione)?

The CAS Registry Number of 8,8'-((1R,2R,3S,4S)-2,4-Bis(3,4-dimethoxyphenyl)cyclobutane-1,3-diyl)bis(1,3-diethyl-7-methyl-3,7-dihydro-1H-purine-2,6-dione) is 702697-27-6.

What is the molecular formula and molecular weight of 8,8'-((1R,2R,3S,4S)-2,4-Bis(3,4-dimethoxyphenyl)cyclobutane-1,3-diyl)bis(1,3-diethyl-7-methyl-3,7-dihydro-1H-purine-2,6-dione)?

8,8'-((1R,2R,3S,4S)-2,4-Bis(3,4-dimethoxyphenyl)cyclobutane-1,3-diyl)bis(1,3-diethyl-7-methyl-3,7-dihydro-1H-purine-2,6-dione) has the molecular formula C40H48N8O8 and a molecular weight of 768.9 g/mol. Its IUPAC name is 8-[3-(1,3-diethyl-7-methyl-2,6-dioxopurin-8-yl)-2,4-bis(3,4-dimethoxyphenyl)cyclobutyl]-1,3-diethyl-7-methylpurine-2,6-dione.

What is 8,8'-((1R,2R,3S,4S)-2,4-Bis(3,4-dimethoxyphenyl)cyclobutane-1,3-diyl)bis(1,3-diethyl-7-methyl-3,7-dihydro-1H-purine-2,6-dione) used for?

8,8'-((1R,2R,3S,4S)-2,4-Bis(3,4-dimethoxyphenyl)cyclobutane-1,3-diyl)bis(1,3-diethyl-7-methyl-3,7-dihydro-1H-purine-2,6-dione) is supplied as a characterised reference material related to Istradefylline. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 8,8'-((1R,2R,3S,4S)-2,4-Bis(3,4-dimethoxyphenyl)cyclobutane-1,3-diyl)bis(1,3-diethyl-7-methyl-3,7-dihydro-1H-purine-2,6-dione) can I order?

We supply 8,8'-((1R,2R,3S,4S)-2,4-Bis(3,4-dimethoxyphenyl)cyclobutane-1,3-diyl)bis(1,3-diethyl-7-methyl-3,7-dihydro-1H-purine-2,6-dione) in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 8,8'-((1R,2R,3S,4S)-2,4-Bis(3,4-dimethoxyphenyl)cyclobutane-1,3-diyl)bis(1,3-diethyl-7-methyl-3,7-dihydro-1H-purine-2,6-dione)?

Yes. Every lot of 8,8'-((1R,2R,3S,4S)-2,4-Bis(3,4-dimethoxyphenyl)cyclobutane-1,3-diyl)bis(1,3-diethyl-7-methyl-3,7-dihydro-1H-purine-2,6-dione) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 8,8'-((1R,2R,3S,4S)-2,4-Bis(3,4-dimethoxyphenyl)cyclobutane-1,3-diyl)bis(1,3-diethyl-7-methyl-3,7-dihydro-1H-purine-2,6-dione) be shipped internationally?

Yes. We export 8,8'-((1R,2R,3S,4S)-2,4-Bis(3,4-dimethoxyphenyl)cyclobutane-1,3-diyl)bis(1,3-diethyl-7-methyl-3,7-dihydro-1H-purine-2,6-dione) worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.