Paclitaxel EP Impurity B

Name: Paclitaxel EP Impurity B
Brand: Vaqora Chemicals
SKU: VQ-027351

About Paclitaxel EP Impurity B

Listed under CAS 71610-00-9, Paclitaxel EP Impurity B is a pharmacopeial impurity of Paclitaxel available from Vaqora Chemicals. With the molecular formula C45H53NO14, it has a molar mass of 831.9 g/mol. Alternative names: Cephalomannine and Paclitaxel - Impurity B.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

As a characterised impurity of Paclitaxel, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer Paclitaxel EP Impurity B in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Paclitaxel

View every impurity, metabolite and intermediate we list for Paclitaxel.

Paclitaxel impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Paclitaxel EP Impurity B
Catalogue No.	VQ-027351
CAS Number	71610-00-9
IUPAC name	[(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-diacetyloxy-1,9-dihydroxy-15-[(2R,3S)-2-hydroxy-3-[[(E)-2-methylbut-2-enoyl]amino]-3-phenylpropanoyl]oxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate
Molecular formula	C₄₅H₅₃NO₁₄
Molecular weight	831.9 g/mol
Exact mass	831.3466
Grade	Reference Standard
HSN code	38229090
InChIKey	DBXFAPJCZABTDR-WBYYIXQISA-N
SMILES	C/C=C(\C)/C(=O)N[C@@H](C1=CC=CC=C1)[C@H](C(=O)O[C@H]2C[C@]3([C@H]([C@H]4[C@@]([C@H](C[C@@H]5[C@]4(CO5)OC(=O)C)O)(C(=O)[C@@H](C(=C2C)C3(C)C)OC(=O)C)C)OC(=O)C6=CC=CC=C6)O)O
PubChem CID	6436208

Physical properties
Physical form	Solid
LogP (XLogP3)	2
H-bond donors / acceptors	4 / 14
TPSA	221 Å²
Synonyms	Cephalomannine, Paclitaxel - Impurity B, Taxol B, N-Debenzoyl-N-tigloylpaclitaxel, N-Debenzoyl-N-tigloylpaclitaxel (Cephalomannine)

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Signal word: Danger

Hazard statements

H315Causes skin irritation
H318Causes serious eye damage
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P354 + P338, P317, P319, P321, P332 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Paclitaxel EP Impurity B?

The CAS Registry Number of Paclitaxel EP Impurity B is 71610-00-9. It is also known as Cephalomannine, Paclitaxel - Impurity B, Taxol B.

What is the molecular formula and molecular weight of Paclitaxel EP Impurity B?

Paclitaxel EP Impurity B has the molecular formula C45H53NO14 and a molecular weight of 831.9 g/mol.

What is Paclitaxel EP Impurity B used for?

Paclitaxel EP Impurity B is supplied as a characterised reference material related to Paclitaxel. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Paclitaxel EP Impurity B can I order?

We supply Paclitaxel EP Impurity B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Paclitaxel EP Impurity B?

Yes. Every lot of Paclitaxel EP Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Paclitaxel EP Impurity B be shipped internationally?

Yes. Paclitaxel EP Impurity B is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.