(R)-Diprophylline

About (R)-Diprophylline

(R)-Diprophylline is a high-purity reference standard of Diprophylline carrying the CAS registry number 72376-78-4. Its molecular formula is C10H14N4O4 and its molecular weight is 254.24 g/mol. The IUPAC name is 7-[(2R)-2,3-dihydroxypropyl]-1,3-dimethylpurine-2,6-dione. Common synonyms include (R)-dyphylline and Diprophylline, (R)-.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Laboratories use this Diprophylline standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, (R)-Diprophylline is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Diprophylline

View every impurity, metabolite and intermediate we list for Diprophylline.

Diprophylline impurities

Specifications & identifiers

Chemical identifiers
Product name	(R)-Diprophylline
Catalogue No.	VQ-048037
CAS Number	72376-78-4
IUPAC name	7-[(2R)-2,3-dihydroxypropyl]-1,3-dimethylpurine-2,6-dione
Molecular formula	C₁₀H₁₄N₄O₄
Molecular weight	254.24 g/mol
Exact mass	254.1015
Grade	Reference Standard
HSN code	38229090
InChIKey	KSCFJBIXMNOVSH-ZCFIWIBFSA-N
SMILES	CN1C2=C(C(=O)N(C1=O)C)N(C=N2)C[C@H](CO)O
PubChem CID	688353

Physical properties
Physical form	Solid
LogP (XLogP3)	-1.8
H-bond donors / acceptors	2 / 5
TPSA	98.9 Å²
Synonyms	(R)-dyphylline, 7-[(2R)-2,3-dihydroxypropyl]-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione, 7-((2R)-2,3-dihydroxypropyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione, Diprophylline, (R)-, [(2R)-1,2-dihydroxy-3-propyl]thiophyllin, 7-[(2R)-2,3-dihydroxypropyl]theophylline, 1H-Purine-2,6-dione, 7-((2R)-2,3-dihydroxypropyl)-3,7-dihydro-1,3-dimethyl-, 1H-Purine-2,6-dione, 7-(2,3-dihydroxypropyl)-3,7-dihydro-1,3-dimethyl-, (R)-, 1,3-dimethyl-7-[(2R)-2,3-dihydroxypropyl]xanthine, 7-[(2R)-2,3-dihydroxypropyl]-1,3-dimethylxanthine, (R)-7-(2,3-dihydroxypropyl)-1,3-dimethyl-1H-purine-2,6(3H,7H)-dione

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (R)-Diprophylline?

The CAS Registry Number of (R)-Diprophylline is 72376-78-4. It is also known as (R)-dyphylline, 7-[(2R)-2,3-dihydroxypropyl]-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione, 7-((2R)-2,3-dihydroxypropyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione.

What is the molecular formula and molecular weight of (R)-Diprophylline?

(R)-Diprophylline has the molecular formula C10H14N4O4 and a molecular weight of 254.24 g/mol. Its IUPAC name is 7-[(2R)-2,3-dihydroxypropyl]-1,3-dimethylpurine-2,6-dione.

What is (R)-Diprophylline used for?

(R)-Diprophylline is supplied as a characterised reference material related to Diprophylline. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (R)-Diprophylline can I order?

We supply (R)-Diprophylline in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (R)-Diprophylline?

Yes. Every lot of (R)-Diprophylline is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (R)-Diprophylline be shipped internationally?

Yes. We export (R)-Diprophylline worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.