Colistin B

About Colistin B

Colistin B is a high-purity reference standard of Colistin carrying the CAS registry number 7239-48-7. Formula C52H98N16O13, molecular weight 1155.4 g/mol. It is also known as Polymyxin E2 Sulfate (Colistin B).

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

As a reference sample of Colistin, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Colistin B is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Colistin

View every impurity, metabolite and intermediate we list for Colistin.

Colistin impurities

Specifications & identifiers

Chemical identifiers
Product name	Colistin B
Catalogue No.	VQ-036440
CAS Number	7239-48-7
IUPAC name	N-[(2S)-4-amino-1-[[(2S,3R)-1-[[(2S)-4-amino-1-oxo-1-[[(3S,6S,9S,12S,15R,18S,21S)-6,9,18-tris(2-aminoethyl)-3-[(1R)-1-hydroxyethyl]-12,15-bis(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclotricos-21-yl]amino]butan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxobutan-2-yl]-6-methylheptanamide
Molecular formula	C₅₂H₉₈N₁₆O₁₃
Molecular weight	1155.4 g/mol
Exact mass	1154.7499
Grade	Reference Standard
HSN code	38229090
InChIKey	KNIWPHSUTGNZST-SSWRVQTPSA-N
SMILES	C[C@H]([C@H]1C(=O)NCC[C@@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N1)CCN)CCN)CC(C)C)CC(C)C)CCN)NC(=O)[C@H](CCN)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCN)NC(=O)CCCCC(C)C)O
PubChem CID	25138298

Physical properties
Physical form	Solid
LogP (XLogP3)	-3.3
H-bond donors / acceptors	18 / 18
TPSA	491 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Colistin B?

The CAS Registry Number of Colistin B is 7239-48-7. It is also known as Polymyxin E2 Sulfate (Colistin B).

What is the molecular formula and molecular weight of Colistin B?

Colistin B has the molecular formula C52H98N16O13 and a molecular weight of 1155.4 g/mol.

What is Colistin B used for?

Colistin B is supplied as a characterised reference material related to Colistin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Colistin B can I order?

We supply Colistin B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Colistin B?

Yes. Every lot of Colistin B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Colistin B be shipped internationally?

Yes. We export Colistin B worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.