2-Amino-5-(4-hydroxy-3,5- dimethoxybenzyl)pyr… 72920-13-9

About 2-Amino-5-(4-hydroxy-3,5- dimethoxybenzyl)pyrimidin-4-ol

2-Amino-5-(4-hydroxy-3,5- dimethoxybenzyl)pyrimidin-4-ol is a metabolite or degradation product of Trimethoprim carrying the CAS registry number 72920-13-9. Its molecular formula is C13H15N3O4 and its molecular weight is 277.28 g/mol. The IUPAC name is 2-amino-5-[(4-hydroxy-3,5-dimethoxyphenyl)methyl]-1H-pyrimidin-6-one.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Trimethoprim, as well as in QC testing and ANDA/DMF documentation. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 2-Amino-5-(4-hydroxy-3,5- dimethoxybenzyl)pyrimidin-4-ol is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Trimethoprim

View every impurity, metabolite and intermediate we list for Trimethoprim.

Trimethoprim impurities

Specifications & identifiers

Chemical identifiers
Product name	2-Amino-5-(4-hydroxy-3,5- dimethoxybenzyl)pyrimidin-4-ol
Catalogue No.	VQ-034442
CAS Number	72920-13-9
IUPAC name	2-amino-5-[(4-hydroxy-3,5-dimethoxyphenyl)methyl]-1H-pyrimidin-6-one
Molecular formula	C₁₃H₁₅N₃O₄
Molecular weight	277.28 g/mol
Exact mass	277.1063
Grade	Reference Standard
HSN code	38229090
InChIKey	GCGONLKCVURQKO-UHFFFAOYSA-N
SMILES	COC1=CC(=CC(=C1O)OC)CC2=CN=C(NC2=O)N
PubChem CID	12577393

Physical properties
Physical form	Solid
LogP (XLogP3)	0.2
H-bond donors / acceptors	3 / 5
TPSA	106 Å²
Synonyms	2-Amino-5-(4-hydroxy-3,5-dimethoxybenzyl)pyrimidin-4(3H)-one, 2-Amino-5-[(4-hydroxy-3,5-dimethoxyphenyl)methyl]-4(3H)-pyrimidinone, 4(1H)-Pyrimidinone, 2-amino-5-[(4-hydroxy-3,5-dimethoxyphenyl)methyl]-, 4(3H)-Pyrimidinone, 2-amino-5-[(4-hydroxy-3,5-dimethoxyphenyl)methyl]-, 5-[(4-hydroxy-3,5-dimethoxyphenyl)methyl]-2-imino-1,2,3,4-tetrahydropyrimidin-4-one

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-Amino-5-(4-hydroxy-3,5- dimethoxybenzyl)pyrimidin-4-ol?

The CAS Registry Number of 2-Amino-5-(4-hydroxy-3,5- dimethoxybenzyl)pyrimidin-4-ol is 72920-13-9. It is also known as 2-Amino-5-(4-hydroxy-3,5-dimethoxybenzyl)pyrimidin-4(3H)-one, 2-Amino-5-[(4-hydroxy-3,5-dimethoxyphenyl)methyl]-4(3H)-pyrimidinone, 4(1H)-Pyrimidinone, 2-amino-5-[(4-hydroxy-3,5-dimethoxyphenyl)methyl]-.

What is the molecular formula and molecular weight of 2-Amino-5-(4-hydroxy-3,5- dimethoxybenzyl)pyrimidin-4-ol?

2-Amino-5-(4-hydroxy-3,5- dimethoxybenzyl)pyrimidin-4-ol has the molecular formula C13H15N3O4 and a molecular weight of 277.28 g/mol. Its IUPAC name is 2-amino-5-[(4-hydroxy-3,5-dimethoxyphenyl)methyl]-1H-pyrimidin-6-one.

What is 2-Amino-5-(4-hydroxy-3,5- dimethoxybenzyl)pyrimidin-4-ol used for?

2-Amino-5-(4-hydroxy-3,5- dimethoxybenzyl)pyrimidin-4-ol is supplied as a characterised reference material related to Trimethoprim. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-Amino-5-(4-hydroxy-3,5- dimethoxybenzyl)pyrimidin-4-ol can I order?

We supply 2-Amino-5-(4-hydroxy-3,5- dimethoxybenzyl)pyrimidin-4-ol in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-Amino-5-(4-hydroxy-3,5- dimethoxybenzyl)pyrimidin-4-ol?

Yes. Every lot of 2-Amino-5-(4-hydroxy-3,5- dimethoxybenzyl)pyrimidin-4-ol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-Amino-5-(4-hydroxy-3,5- dimethoxybenzyl)pyrimidin-4-ol be shipped internationally?

Yes. 2-Amino-5-(4-hydroxy-3,5- dimethoxybenzyl)pyrimidin-4-ol is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.