Methylnaltrexone Bromide
Synonyms: N-Methylnaltrexone Bromide · Naltrexone methobromide · MRZ-2663BR · MOA-728
Methylnaltrexone Bromide (CAS 73232-52-7) – Naltrexone reference standard. C21H26BrNO4, MW 436.3. Order from Vaqora Chemicals with COA and global delivery.
About Methylnaltrexone Bromide
Vaqora Chemicals supplies Methylnaltrexone Bromide, a high-purity reference standard of Naltrexone registered under CAS number 73232-52-7. Its molecular formula is C21H26BrNO4 and its molecular weight is 436.3 g/mol. Common synonyms include N-Methylnaltrexone Bromide and Naltrexone methobromide.
It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.
Laboratories use this Naltrexone standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.
Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Methylnaltrexone Bromide is dispatched with a Certificate of Analysis (COA) to destinations worldwide.
Typical applications
- Identification & assay
- Method development & validation
- QC reference material
- Fine chemical synthesis
Industries
View every impurity, metabolite and intermediate we list for Naltrexone.
Naltrexone impuritiesSpecifications & identifiers
| Product name | Methylnaltrexone Bromide |
|---|---|
| Catalogue No. | VQ-038550 |
| CAS Number | 73232-52-7 |
| IUPAC name | (4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-3-methyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-3-ium-7-one bromide |
| Molecular formula | C21H26BrNO4 |
| Molecular weight | 436.3 g/mol |
| Exact mass | 435.1045 |
| Grade | Reference Standard |
| HSN code | 38229090 |
| InChIKey | IFGIYSGOEZJNBE-KNLJMPJLSA-N |
| SMILES | C[N+]1(CC[C@]23[C@@H]4C(=O)CC[C@]2([C@H]1CC5=C3C(=C(C=C5)O)O4)O)CC6CC6.[Br-] |
| PubChem CID | 5361917 |
| Physical form | Solid |
|---|---|
| H-bond donors / acceptors | 2 / 5 |
| TPSA | 66.8 Ų |
| Synonyms | N-Methylnaltrexone Bromide, Naltrexone methobromide, MRZ-2663BR, MOA-728, bromuro de metilnaltrexona, bromure de methylnaltrexone, methylnaltrexoni bromidum, N-Methyl Naltrexone Bromide, MRZ 2663BR, Naltrexone Methyl Bromide |
Safety & hazard information (GHS)
Signal word: Danger
Hazard statements
H301Toxic if swallowedH302Harmful if swallowedH312Harmful in contact with skinH317May cause an allergic skin reactionH332Harmful if inhaledH334May cause allergy or asthma symptoms or breathing difficulties if inhaledH400Very toxic to aquatic life
Precautionary statements: P233, P260, P261, P264, P270, P271, P272, P273, P280, P284, P301 + P316, P301 + P317, P302 + P352, P304 + P340, P317, P321, P330, P333 + P317, P342 + P316, P362 + P364, P391, P403, P405, P501
Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.
Documents
Frequently asked questions
What is the CAS number of Methylnaltrexone Bromide?
The CAS Registry Number of Methylnaltrexone Bromide is 73232-52-7. It is also known as N-Methylnaltrexone Bromide, Naltrexone methobromide, MRZ-2663BR.
What is the molecular formula and molecular weight of Methylnaltrexone Bromide?
Methylnaltrexone Bromide has the molecular formula C21H26BrNO4 and a molecular weight of 436.3 g/mol. Its IUPAC name is (4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-3-methyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-3-ium-7-one bromide.
What is Methylnaltrexone Bromide used for?
Methylnaltrexone Bromide is supplied as a characterised reference material related to Naltrexone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.
Which grade and pack sizes of Methylnaltrexone Bromide can I order?
We supply Methylnaltrexone Bromide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.
Do you provide a COA and SDS with Methylnaltrexone Bromide?
Yes. Every lot of Methylnaltrexone Bromide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.
Can Methylnaltrexone Bromide be shipped internationally?
Yes. Methylnaltrexone Bromide is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.
Enquire about Methylnaltrexone Bromide
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