N-Nitroso Quetiapine HEEP Impurity

Name: N-Nitroso Quetiapine HEEP Impurity
Brand: Vaqora Chemicals
SKU: VQ-021295

About N-Nitroso Quetiapine HEEP Impurity

N-Nitroso Quetiapine HEEP Impurity (CAS 73486-81-4) is a nitrosamine impurity of Quetiapine offered by Vaqora Chemicals. Its molecular formula is C8H17N3O3 and its molecular weight is 203.24 g/mol. Its systematic (IUPAC) name is 2-[2-(4-nitrosopiperazin-1-yl)ethoxy]ethanol. Common synonyms include Quetiapine impurity 64 and 2-[2-(4-Nitroso-1-piperazinyl)ethoxy]ethanol.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

It is used as a reference standard for trace-level detection and quantitation of nitrosamine impurities by LC-MS/MS or GC-MS, supporting nitrosamine risk assessments for Quetiapine, method validation (AMV) and regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, N-Nitroso Quetiapine HEEP Impurity is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Nitrosamine risk assessment
Trace LC-MS/MS quantitation
Method validation (AMV)
Regulatory submissions

Industries

Related to Quetiapine

View every impurity, metabolite and intermediate we list for Quetiapine.

Quetiapine impurities

Specifications & identifiers

Chemical identifiers
Product name	N-Nitroso Quetiapine HEEP Impurity
Catalogue No.	VQ-021295
CAS Number	73486-81-4
IUPAC name	2-[2-(4-nitrosopiperazin-1-yl)ethoxy]ethanol
Molecular formula	C₈H₁₇N₃O₃
Molecular weight	203.24 g/mol
Exact mass	203.127
Grade	Reference Standard
HSN code	38229090
InChIKey	ZCSHCPJVAISBPO-UHFFFAOYSA-N
SMILES	C1CN(CCN1CCOCCO)N=O
PubChem CID	170916121

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.8
H-bond donors / acceptors	1 / 6
TPSA	65.4 Å²
Synonyms	2-(2-(4-nitrosopiperazin-1-yl)ethoxy)ethan-1-ol, 2-[2-(4-Nitrosopiperazin-1-yl)ethoxy]ethan-1-ol, Quetiapine impurity 64, 2-[2-(4-Nitroso-1-piperazinyl)ethoxy]ethanol, Ethanol, 2-[2-(4-nitroso-1-piperazinyl)ethoxy]-, N-Nitroso Quetiapine, Quetiapine Impurity 42, Quetiapine Nitroso Impurity

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H302+H312+H332Harmful if swallowed, in contact with skin or if inhaled
H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H318Causes serious eye damage
H332Harmful if inhaled
H335May cause respiratory irritation
H351Suspected of causing cancer
H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements: P203, P260, P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P354 + P338, P317, P318, P319, P321, P330, P332 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Nitroso Quetiapine HEEP Impurity?

The CAS Registry Number of N-Nitroso Quetiapine HEEP Impurity is 73486-81-4. It is also known as 2-(2-(4-nitrosopiperazin-1-yl)ethoxy)ethan-1-ol, 2-[2-(4-Nitrosopiperazin-1-yl)ethoxy]ethan-1-ol, Quetiapine impurity 64.

What is the molecular formula and molecular weight of N-Nitroso Quetiapine HEEP Impurity?

N-Nitroso Quetiapine HEEP Impurity has the molecular formula C8H17N3O3 and a molecular weight of 203.24 g/mol. Its IUPAC name is 2-[2-(4-nitrosopiperazin-1-yl)ethoxy]ethanol.

What is N-Nitroso Quetiapine HEEP Impurity used for?

N-Nitroso Quetiapine HEEP Impurity is supplied as a characterised reference material related to Quetiapine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Nitroso Quetiapine HEEP Impurity can I order?

We supply N-Nitroso Quetiapine HEEP Impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Nitroso Quetiapine HEEP Impurity?

Yes. Every lot of N-Nitroso Quetiapine HEEP Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Nitroso Quetiapine HEEP Impurity be shipped internationally?

Yes. N-Nitroso Quetiapine HEEP Impurity is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.