Tramadol EP Impurity A (Hydrochloride Salt)

Name: Tramadol EP Impurity A (Hydrochloride Salt)
Brand: Vaqora Chemicals
SKU: VQ-006742

About Tramadol EP Impurity A (Hydrochloride Salt)

Tramadol EP Impurity A (Hydrochloride Salt) (CAS 73806-49-2) is a pharmacopeial impurity of Tramadol offered by Vaqora Chemicals. With the molecular formula C16H26ClNO2, it has a molar mass of 299.83 g/mol. The IUPAC name is trans-(1R,2S)-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexan-1-ol. Hydrochloride. Alternative names: Tramadol Impurity A (Hydrochloride Salt) and rel (1R,2S)-Tramadol Hydrochloride.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

As a characterised impurity of Tramadol, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Tramadol

View every impurity, metabolite and intermediate we list for Tramadol.

Tramadol impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Tramadol EP Impurity A (Hydrochloride Salt)
Catalogue No.	VQ-006742
CAS Number	73806-49-2
Other CAS	152538-36-8
IUPAC name	trans-(1R,2S)-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexan-1-ol;hydrochloride
Molecular formula	C₁₆H₂₆ClNO₂
Molecular weight	299.83 g/mol
Exact mass	299.1652
Grade	Reference Standard
HSN code	38229090
InChIKey	PPKXEPBICJTCRU-DMLYUBSXSA-N
SMILES	CN(C)C[C@@H]1CCCC[C@@]1(C2=CC(=CC=C2)OC)O.Cl
PubChem CID	63014

Physical properties
Physical form	Solid
H-bond donors / acceptors	2 / 3
TPSA	32.7 Å²
Synonyms	Tramadol Impurity A (Hydrochloride Salt), rel (1R,2S)-Tramadol Hydrochloride, (1R,2S)-Tramadol Hydrochloride, trans-Tramadol hydrochloride, 2-((dimethylamino)methyl)-1-(m-methoxyphenyl)-1-cyclohexanohydrochloride, (1R,2R)-2-((dimethylamino)methyl)-1-(3-methoxyphenyl)cyclohexanohydrochloride, Crispin, Tramadol hydrochloride, trans-, Cyclohexanol, 2-((dimethylamino)methyl)-1-(3-methoxyphenyl)-, hydrochloride, (1R,2S)-rel-, Cyclohexanol, 2-((dimethylamino)methyl)-1-(3-methoxyphenyl)-, hydrochloride, trans-, Cyclohexanol, 2-((dimethylamino)methyl)-1-(m-methoxyphenyl)-, hydrochloride, (E)-, Cyclohexanol, 2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)-, hydrochloride, (1R,2S)-rel-

Safety & hazard information (GHS)

Toxic

Harmful / irritant

Environmental hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H302Harmful if swallowed
H411Toxic to aquatic life with long lasting effects

Precautionary statements: P264, P270, P273, P301 + P316, P301 + P317, P321, P330, P391, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Tramadol EP Impurity A (Hydrochloride Salt)?

The CAS Registry Number of Tramadol EP Impurity A (Hydrochloride Salt) is 73806-49-2. It is also known as Tramadol Impurity A (Hydrochloride Salt), rel (1R,2S)-Tramadol Hydrochloride, (1R,2S)-Tramadol Hydrochloride.

What is the molecular formula and molecular weight of Tramadol EP Impurity A (Hydrochloride Salt)?

Tramadol EP Impurity A (Hydrochloride Salt) has the molecular formula C16H26ClNO2 and a molecular weight of 299.83 g/mol.

What is Tramadol EP Impurity A (Hydrochloride Salt) used for?

Tramadol EP Impurity A (Hydrochloride Salt) is supplied as a characterised reference material related to Tramadol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Tramadol EP Impurity A (Hydrochloride Salt) can I order?

We supply Tramadol EP Impurity A (Hydrochloride Salt) in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Tramadol EP Impurity A (Hydrochloride Salt)?

Yes. Every lot of Tramadol EP Impurity A (Hydrochloride Salt) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Tramadol EP Impurity A (Hydrochloride Salt) be shipped internationally?

Yes. Tramadol EP Impurity A (Hydrochloride Salt) is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.